{"product_id":"advant-tablets-16mg","title":"Advant Tablets 16mg","description":"\u003cp\u003eAdvant Tablets 16mg\u003c\/p\u003e\n\u003cp\u003eAdvant Tablets Specification Sheet\u003cbr\u003e________________________________________\u003cbr\u003eRequires Prescription: ✅ YES\u003cbr\u003eGeneric Name: Candesartan Cilexetil\u003cbr\u003eUsed For: Treatment of Hypertension (high blood pressure)\u003cbr\u003e________________________________________\u003cbr\u003eHow It Works\u003cbr\u003eCandesartan is an angiotensin II receptor blocker (ARB).\u003cbr\u003e•    Angiotensin II, formed via ACE (kininase II), causes vasoconstriction, aldosterone secretion, cardiac stimulation, and sodium retention.\u003cbr\u003e•    Candesartan selectively blocks AT1 receptors in vascular smooth muscle and adrenal glands, reducing blood pressure by preventing vasoconstriction and aldosterone release.\u003cbr\u003e•    Its effect is independent of the synthesis pathway of angiotensin II.\u003cbr\u003e________________________________________\u003cbr\u003eUsage and Dosage\u003cbr\u003e•    Active Ingredient: Candesartan Cilexetil\u003cbr\u003e•    Dosage: As prescribed by a healthcare professional, tailored to patient age and condition\u003cbr\u003e•    Age Range: Adults and children aged 1 to \u0026lt;17 years\u003cbr\u003e________________________________________\u003cbr\u003eSide Effects\u003cbr\u003eGeneral:\u003cbr\u003e•    Asthenia (weakness), fever\u003cbr\u003eNervous System:\u003cbr\u003e•    Paresthesia, vertigo\u003cbr\u003eGastrointestinal:\u003cbr\u003e•    Dyspepsia (indigestion), gastroenteritis\u003cbr\u003eCardiac:\u003cbr\u003e•    Tachycardia, palpitations\u003cbr\u003eMetabolic:\u003cbr\u003e•    Increased creatine phosphokinase, hyperglycemia, hypertriglyceridemia, hyperuricemia\u003cbr\u003eMusculoskeletal:\u003cbr\u003e•    Myalgia (muscle pain)\u003cbr\u003eHematologic:\u003cbr\u003e•    Epistaxis (nosebleeds)\u003cbr\u003ePsychiatric:\u003cbr\u003e•    Anxiety, depression, somnolence (drowsiness)\u003c\/p\u003e\n\u003cp\u003eRespiratory:\u003cbr\u003e•    Dyspnea (shortness of breath)\u003cbr\u003eSkin:\u003cbr\u003e•    Rash, increased sweating\u003cbr\u003eUrinary:\u003cbr\u003e•    Hematuria (blood in urine)\u003cbr\u003e________________________________________\u003cbr\u003eDrug Interactions\u003cbr\u003eUse with caution when combined with:\u003cbr\u003e•    Glyburide, Nifedipine, Digoxin, Warfarin\u003cbr\u003e•    Hydrochlorothiazide, Oral contraceptives\u003cbr\u003e•    ACE Inhibitors (e.g., Enalapril)\u003cbr\u003e•    Potassium-sparing diuretics, Potassium supplements, Heparin\u003cbr\u003e________________________________________\u003cbr\u003eContraindications (When Not to Use)\u003cbr\u003eDo not use in patients who are:\u003cbr\u003e•    Hypersensitive to candesartan or any of its components\u003cbr\u003e________________________________________\u003cbr\u003ePrecautions\u003cbr\u003e•    Excessive blood pressure drop in patients with ischemic heart or cerebrovascular disease can lead to myocardial infarction or stroke\u003cbr\u003e________________________________________\u003cbr\u003eWarnings\u003cbr\u003e1.    Hypotension may occur, especially in patients with heart failure or volume depletion. Carefully monitor and correct fluid loss before starting.\u003cbr\u003e2.    May increase blood urea and creatinine in patients with bilateral renal artery stenosis or a single kidney.\u003cbr\u003e3.    In dialysis patients, blood pressure may be highly sensitive to candesartan. Titrate dose carefully and monitor BP closely.\u003cbr\u003e________________________________________\u003cbr\u003ePregnancy Category\u003cbr\u003e•    ⚠️ Always consult your physician before use, especially during pregnancy or breastfeeding\u003cbr\u003e________________________________________\u003cbr\u003eStorage\u003cbr\u003e✅ Yes — Store at room temperature, away from direct light and heat\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53199320383819,"sku":null,"price":605.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_6751.jpg?v=1755520015","url":"https:\/\/wellnesspharmacy.pk\/products\/advant-tablets-16mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}