{"product_id":"artem-ds-tablets-80-480mg","title":"Artem Ds Tablets 80\/480mg","description":"\u003cp\u003eMedicine Name: Artem-Ds Plus Tablets 80\/480mg\u003c\/p\u003e\n\u003cp\u003eArtem-Ds Plus Specification Sheet\u003cbr\u003e________________________________________\u003cbr\u003eRequires Prescription: ✅ Yes\u003cbr\u003eGenerics: Artemether and Lumefantrine\u003cbr\u003eUsed For: Treatment of Malaria\u003cbr\u003e________________________________________\u003cbr\u003eHow It Works\u003cbr\u003e•    Artemether contains an endoperoxide bridge that generates cytotoxic free radicals in the malarial parasite, damaging and killing it.\u003cbr\u003e•    Lumefantrine works by interfering with the conversion of heme to hemozoin in the parasite, which is essential for its survival.\u003cbr\u003e•    Together, they act on different stages of the parasite lifecycle for effective clearance.\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003eIndications\u003cbr\u003e•    Treatment of uncomplicated malaria, particularly Plasmodium falciparum infections.\u003cbr\u003e•    Effective against drug-resistant strains when used as recommended.\u003cbr\u003e________________________________________\u003cbr\u003eDosage\u003cbr\u003e•    Active Ingredients: Artemether + Lumefantrine\u003cbr\u003e•    Must be taken with fatty food for optimal absorption.\u003cbr\u003e•    Dosage as prescribed by a healthcare professional, usually in a six-dose schedule over 3 days.\u003cbr\u003e________________________________________\u003cbr\u003eSide Effects\u003cbr\u003eVery Common:\u003cbr\u003e•    Palpitations, headache, dizziness\u003cbr\u003e•    Abdominal pain, nausea, vomiting, anorexia\u003cbr\u003e•    Arthralgia, myalgia, asthenia (weakness), fatigue\u003cbr\u003e•    Sleep disturbances\u003cbr\u003eCommon:\u003cbr\u003e•    Diarrhea, rash, cough, insomnia\u003cbr\u003e•    Pruritus (itching), amnesia, paraesthesia\u003cbr\u003e•    Gait disturbances, QT prolongation on ECG\u003cbr\u003eUncommon:\u003cbr\u003e•    Elevated liver enzymes\u003cbr\u003e•    Neurological symptoms: clonus, ataxia, hypoesthesia, somnolence\u003cbr\u003e________________________________________\u003cbr\u003eDrug Interactions\u003cbr\u003eAvoid concurrent use with drugs that affect CYP3A4 or CYP2D6, such as:\u003cbr\u003e•    CYP3A4 inhibitors: erythromycin, ketoconazole, itraconazole, cimetidine, HIV protease inhibitors\u003cbr\u003e•    CYP2D6 inhibitors: flecainide, metoprolol, imipramine, amitriptyline\u003cbr\u003e•    Mefloquine – may reduce the bioavailability of lumefantrine\u003cbr\u003e________________________________________\u003cbr\u003eWhen Not to Use\u003cbr\u003e•    Hypersensitivity to artemether or lumefantrine\u003cbr\u003e•    Avoid use if there's a history of cardiac arrhythmia or QT prolongation\u003cbr\u003e________________________________________\u003cbr\u003ePrecautions\u003cbr\u003e•    Avoid combining with other antimalarials unless absolutely necessary\u003cbr\u003e•    Use with extreme caution in patients with:\u003cbr\u003eo    Severe renal or hepatic impairment\u003cbr\u003eo    Cardiac disorders\u003cbr\u003eo    Electrolyte imbalances\u003cbr\u003e________________________________________\u003cbr\u003eWarnings\u003cbr\u003eWarning 1:\u003cbr\u003ePatients with renal, hepatic, or cardiac conditions require close ECG monitoring and electrolyte correction before and during treatment.\u003cbr\u003eWarning 2:\u003cbr\u003eCaution when combining with other CYP3A4-metabolized drugs, as therapeutic levels may be altered.\u003cbr\u003eWarning 3:\u003cbr\u003ePatients unable to consume food during treatment should be closely monitored, as treatment failure or recrudescence risk increases with reduced drug absorption.\u003cbr\u003e________________________________________\u003cbr\u003ePregnancy Category\u003cbr\u003e⚠️ Always consult a physician before use during pregnancy or breastfeeding\u003cbr\u003e________________________________________\u003cbr\u003eStorage\u003cbr\u003e✅ Yes — Store at room temperature, away from direct light and heat\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53199224144203,"sku":null,"price":650.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_6745.jpg?v=1755519065","url":"https:\/\/wellnesspharmacy.pk\/products\/artem-ds-tablets-80-480mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}