{"product_id":"celbex-100mg-capsules","title":"Celbex 100MG Capsules","description":"\u003cp\u003eMedicine Name: Celbexx Capsules 100mg\u003cbr\u003eCelbexx Capsules Specification\u003cbr\u003e Requires Prescription: Yes\u003cbr\u003e Generic Name: Celecoxib\u003cbr\u003e Used For: Pain \u0026amp; Inflammation\u003cbr\u003eHow It Works\u003cbr\u003eCelecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID).\u003cbr\u003e It reduces pain, inflammation, and fever by inhibiting cyclooxygenase-2 (COX-2), an\u003cbr\u003eenzyme involved in prostaglandin synthesis.\u003cbr\u003e At therapeutic doses, it does not significantly inhibit COX-1, minimizing gastric side\u003cbr\u003eeffects compared to traditional NSAIDs.\u003cbr\u003eUsage and Safety\u003cbr\u003e Dosage: As prescribed by a physician; contains Celecoxib.\u003cbr\u003eCommon Side Effects:\u003cbr\u003e Gastrointestinal: Abdominal pain, diarrhea, dyspepsia, flatulence, nausea\u003cbr\u003e Nervous System: Dizziness, headache\u003cbr\u003e Respiratory: Sinusitis, pharyngitis, rhinitis\u003cbr\u003e Others: Back pain, insomnia, rash\u003cbr\u003eLess Common to Rare Side Effects:\u003cbr\u003e GI: Constipation, gastritis, reflux, bleeding\u003cbr\u003e Cardio: Hypertension, angina, heart attack\u003cbr\u003e Resp: Bronchospasm, pneumonia\u003cbr\u003e Nervous: Migraines, vertigo, paresthesia\u003cbr\u003e Psychiatric: Anxiety, depression, insomnia\u003cbr\u003e Very rare: Heart failure, stroke, kidney failure, liver toxicity, blood disorders (e.g.,\u003cbr\u003eaplastic anemia), skin reactions (e.g., Stevens-Johnson syndrome)\u003cbr\u003eDrug Interactions\u003cbr\u003eUse with caution or avoid combining with:\u003cbr\u003e ACE inhibitors \/ ARBs (e.g., for blood pressure)\u003cbr\u003e Diuretics (e.g., furosemide, thiazides)\u003cbr\u003e Aspirin and other NSAIDs\u003cbr\u003e Fluconazole, Warfarin (increased bleeding risk)\u003cbr\u003e Lithium (can increase lithium levels)\u003cbr\u003e Antacids, glucocorticoids\u003cbr\u003eIndications\u003cbr\u003eCelecoxib is used for:\u003cbr\u003e1. Osteoarthritis – pain and inflammation\u003cbr\u003e2. Rheumatoid arthritis (adults)\u003cbr\u003e3. Ankylosing spondylitis\u003cbr\u003e4. Juvenile rheumatoid arthritis (age ≥2 years)\u003cbr\u003e5. Acute pain in adults, including post-operative pain\u003cbr\u003eContraindications (When Not to Use)\u003cbr\u003eDo not use in patients with:\u003cbr\u003e Allergy to celecoxib, sulfonamides, or NSAIDs\u003cbr\u003e History of asthma or allergic reactions to aspirin\/NSAIDs\u003cbr\u003e Severe liver or kidney impairment\u003cbr\u003e History of heart attack, stroke, heart failure, or GI bleeding\u003cbr\u003e Use before or after coronary artery bypass (CABG) surgery\u003cbr\u003e Peptic ulcer, inflammatory bowel disease, or bleeding disorders\u003cbr\u003ePrecautions\u003cbr\u003e Do not substitute for corticosteroids in steroid-dependent patients\u003cbr\u003e Taper corticosteroids gradually to avoid adrenal insufficiency if discontinuing\u003cbr\u003e Caution in patients with fluid retention, hypertension, or cardiac disease\u003cbr\u003eWarnings\u003cbr\u003e1. Edema \u0026amp; fluid retention can worsen heart failure or hypertension.\u003cbr\u003e2. Celecoxib may raise blood pressure or worsen existing hypertension.\u003cbr\u003e3. Liver toxicity: Monitor liver function; stop if signs of liver damage appear (e.g.,\u003cbr\u003ejaundice, rash, eosinophilia).\u003cbr\u003eAdditional Information\u003cbr\u003e Pregnancy Category: Always consult a physician before use\u003cbr\u003e Storage: Yes — Store at room temperature, away from heat and light\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53275074560331,"sku":null,"price":475.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7214.jpg?v=1756460733","url":"https:\/\/wellnesspharmacy.pk\/products\/celbex-100mg-capsules","provider":"The Wellness Hospital","version":"1.0","type":"link"}