{"product_id":"celbex-200mg-capsules","title":"Celbex 200MG Capsules","description":"\u003cp\u003e Medicine Name: Celbexx Capsules 200mg\u003cbr\u003eCelbexx Capsules Specification Sheet\u003cbr\u003eBasic Information\u003cbr\u003eRequires Prescription Yes\u003cbr\u003eGeneric Name Celecoxib\u003cbr\u003eUsed For Pain \u0026amp; Inflammation\u003cbr\u003eMechanism of Action\u003cbr\u003e Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID).\u003cbr\u003e It inhibits prostaglandin synthesis, primarily by blocking COX-2 enzyme.\u003cbr\u003e At therapeutic doses, it does not inhibit COX-1, reducing gastrointestinal side effects.\u003cbr\u003eIndications\u003cbr\u003e1. Osteoarthritis\u003cbr\u003e2. Rheumatoid arthritis (Adults)\u003cbr\u003e3. Ankylosing spondylitis\u003cbr\u003e4. Juvenile rheumatoid arthritis (≥2 years)\u003cbr\u003e5. Acute pain in adults, including postoperative pain\u003cbr\u003eDosage\u003cbr\u003e Active Ingredient: Celecoxib\u003cbr\u003e Dosage varies based on condition and patient profile. Follow physician’s prescription.\u003cbr\u003eSide Effects\u003cbr\u003eCommon:\u003cbr\u003e Gastrointestinal: Abdominal pain, diarrhea, flatulence, nausea, dyspepsia\u003cbr\u003e Neurological: Dizziness, headache\u003cbr\u003e Respiratory: Pharyngitis, sinusitis, upper respiratory infections\u003cbr\u003e Others: Rash, insomnia, back pain\u003cbr\u003eLess Common:\u003cbr\u003e GI: Constipation, reflux, vomiting\u003cbr\u003e Cardiac: Palpitations, angina, hypertension\u003cbr\u003e CNS: Vertigo, paresthesia, leg cramps\u003cbr\u003e Psychiatric: Anxiety, somnolence, depression\u003cbr\u003e Respiratory: Bronchitis, coughing, pneumonia\u003cbr\u003eVery Rare (Serious):\u003cbr\u003e Heart failure, stroke, pulmonary embolism\u003cbr\u003e Severe skin reactions: Stevens-Johnson syndrome, toxic epidermal necrolysis\u003cbr\u003e Hepatitis, pancreatitis, renal failure, aplastic anemia, agranulocytosis\u003cbr\u003e Anaphylactoid reactions, angioedema\u003cbr\u003eContraindications (Do NOT Use If):\u003cbr\u003e Allergic to celecoxib, sulfonamides, or NSAIDs\u003cbr\u003e History of asthma, urticaria, or anaphylaxis from NSAIDs\u003cbr\u003e Severe liver or kidney impairment (Child-Pugh Class C or CrCl \u0026lt;30 mL\/min)\u003cbr\u003e Active GI bleeding or ulcers\u003cbr\u003e History of myocardial infarction, stroke, or heart failure\u003cbr\u003e During CABG surgery (perioperative use)\u003cbr\u003e Inflammatory bowel disease\u003cbr\u003eDrug Interactions\u003cbr\u003eUse caution with:\u003cbr\u003e ACE inhibitors, ARBs (e.g., for blood pressure)\u003cbr\u003e Diuretics: Furosemide, thiazides\u003cbr\u003e Aspirin, Warfarin, Glucocorticoids (↑ GI\/bleeding risk)\u003cbr\u003e Lithium, Fluconazole, Antacids\u003cbr\u003ePrecautions\u003cbr\u003e Not a corticosteroid substitute. Avoid abrupt corticosteroid withdrawal.\u003cbr\u003e Taper corticosteroids gradually under supervision.\u003cbr\u003eWarnings\u003cbr\u003e1. May cause fluid retention or worsen heart failure and hypertension\u003cbr\u003e2. Risk of cardiovascular events (MI, stroke) — monitor blood pressure\u003cbr\u003e3. Liver monitoring recommended if signs of liver dysfunction occur\u003cbr\u003eAdditional Information\u003cbr\u003ePregnancy Category Always consult a physician before use\u003cbr\u003eStorage Yes — Store at room temperature, away from direct light and heat\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53275138261323,"sku":null,"price":745.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7194.jpg?v=1756461569","url":"https:\/\/wellnesspharmacy.pk\/products\/celbex-200mg-capsules","provider":"The Wellness Hospital","version":"1.0","type":"link"}