{"product_id":"combivair-rotacaps-capsules-400-6mcg","title":"Combivair Rotacaps Capsules 400\/6mcg","description":"\u003cp\u003eCombivair Rotacaps – Product Specification Sheet\u003cbr\u003e1. Basic Information\u003cbr\u003e Prescription Required: ✅ Yes\u003cbr\u003e Generic Components: Formoterol Fumarate, Budesonide\u003cbr\u003e Used For:\u003cbr\u003eo Asthma\u003cbr\u003eo Maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD)\u003cbr\u003e2. Mechanism of Action\u003cbr\u003e Budesonide:\u003cbr\u003eA glucocorticosteroid with a dose-dependent anti-inflammatory effect in the airways.\u003cbr\u003eReduces symptoms and exacerbations. Inhaled use results in fewer systemic side effects\u003cbr\u003ecompared to oral corticosteroids.\u003cbr\u003e Formoterol:\u003cbr\u003eA selective β2-adrenoceptor agonist. Provides rapid (within 1–3 minutes) and longlasting (≥12 hours) bronchodilation by relaxing bronchial smooth muscle.\u003cbr\u003e3. Dosage\u003cbr\u003e Contains both Formoterol Fumarate and Budesonide in fixed-dose combination\u003cbr\u003e(individual dosages per capsule depend on the strength prescribed).\u003cbr\u003e4. Side Effects\u003cbr\u003e Common:\u003cbr\u003eo Oral thrush (Candida), headache, tremor\u003cbr\u003eo Palpitations, hoarseness, coughing, throat irritation\u003cbr\u003e Uncommon:\u003cbr\u003eo Anxiety, aggression, sleep disturbances\u003cbr\u003eo Dizziness, nausea, bruising, muscle cramps\u003cbr\u003e Rare:\u003cbr\u003eo Allergic reactions (rash, urticaria, anaphylaxis)\u003cbr\u003eo Cardiac arrhythmias, bronchospasm, hypokalemia\u003cbr\u003e Very Rare:\u003cbr\u003eo Cushing's syndrome, adrenal suppression\u003cbr\u003eo Growth retardation, osteoporosis, hyperglycemia\u003cbr\u003eo Glaucoma, cataracts, depression, QTc prolongation\u003cbr\u003e5. Drug Interactions\u003cbr\u003eAvoid concurrent use with:\u003cbr\u003e CYP3A4 inhibitors: (e.g., ketoconazole, itraconazole, HIV protease inhibitors)\u003cbr\u003e Beta-blockers: (including eye drops)\u003cbr\u003e Antiarrhythmics: (quinidine, procainamide)\u003cbr\u003e Antidepressants: (TCAs, MAOIs)\u003cbr\u003e Others: L-Dopa, L-thyroxine, oxytocin, alcohol, loop\/thiazide diuretics\u003cbr\u003e6. Contraindications\u003cbr\u003e Known hypersensitivity to Budesonide, Formoterol, or excipients\u003cbr\u003e Not for primary treatment of status asthmaticus or acute exacerbations requiring\u003cbr\u003eintensive intervention\u003cbr\u003e7. Precautions\u003cbr\u003e Long-term use of inhaled corticosteroids may increase risk of glaucoma and cataracts\u003cbr\u003e Monitor patients with a history of ocular hypertension\u003cbr\u003e8. Warnings\u003cbr\u003e1. Not for acute asthma\/COPD episodes – do not use as a rescue inhaler\u003cbr\u003e2. Avoid additional LABA use – risk of serious cardiovascular side effects\u003cbr\u003e3. Systemic steroid effects may occur at high or prolonged doses; taper slowly if\u003cbr\u003ediscontinuing\u003cbr\u003e9. Additional Information\u003cbr\u003e Pregnancy Category: Consult your physician before use\u003cbr\u003e Storage: ✅ Yes\u003cbr\u003eo Store at room temperature\u003cbr\u003eo Keep away from direct heat and light\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53279709266251,"sku":null,"price":175.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7183.jpg?v=1756521919","url":"https:\/\/wellnesspharmacy.pk\/products\/combivair-rotacaps-capsules-400-6mcg","provider":"The Wellness Hospital","version":"1.0","type":"link"}