{"product_id":"diampa-lt-tablets-25mg-5mg","title":"Diampa Lt Tablets 25mg+5mg","description":"\u003cp\u003eMedicine Name: Diampa Lt Tablets 25mg+5mg\u003c\/p\u003e\n\u003cp\u003e📋 Diampa LT Tablets – Product Specification\u003cbr\u003e________________________________________\u003cbr\u003e💊 Requires Prescription:\u003cbr\u003eYes\u003cbr\u003e________________________________________\u003cbr\u003e🧪 Generics:\u003cbr\u003eEmpagliflozin + Linagliptin\u003cbr\u003e________________________________________\u003cbr\u003e🔍 Used For:\u003cbr\u003eType 2 Diabetes Mellitus\u003cbr\u003e________________________________________\u003cbr\u003e⚙️ How It Works:\u003cbr\u003eEmpagliflozin (SGLT2 Inhibitor):\u003cbr\u003e•    Blocks sodium-glucose co-transporter 2 (SGLT2) in the kidneys\u003cbr\u003e•    Reduces glucose reabsorption from the renal tubules\u003cbr\u003e•    Increases urinary glucose excretion, lowering blood glucose levels\u003cbr\u003eLinagliptin (DPP-4 Inhibitor):\u003cbr\u003e•    Inhibits the enzyme DPP-4, which degrades incretin hormones (GLP-1 and GIP)\u003cbr\u003e•    Enhances insulin secretion and reduces glucagon levels in a glucose-dependent manner\u003cbr\u003e•    Supports glycemic control by increasing insulin and decreasing hepatic glucose production\u003cbr\u003e________________________________________\u003cbr\u003e📦 Dosage:\u003cbr\u003eEmpagliflozin + Linagliptin\u003cbr\u003e(Exact dosage should be prescribed by a healthcare professional.)\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e⚠️ Side Effects:\u003cbr\u003e•    Common:\u003cbr\u003eo    Urinary tract infections (including pyelonephritis, urosepsis)\u003cbr\u003eo    Genital infections (e.g., vulvovaginitis, balanitis)\u003cbr\u003eo    Nasopharyngitis\u003cbr\u003eo    Hypoglycemia (especially with insulin or sulfonylurea)\u003cbr\u003eo    Increased urination, thirst, rash, pruritus, cough\u003cbr\u003eo    Elevated amylase and lipase levels\u003cbr\u003e•    Uncommon:\u003cbr\u003eo    Hypersensitivity reactions (e.g., urticaria, angioedema)\u003cbr\u003eo    Pancreatitis, volume depletion, dysuria\u003cbr\u003eo    Increases in hematocrit, serum lipids, and creatinine\u003cbr\u003e•    Rare\/Not Known:\u003cbr\u003eo    Fournier's gangrene (necrotizing fasciitis of the perineum)\u003cbr\u003eo    Bullous pemphigoid\u003cbr\u003e________________________________________\u003cbr\u003e🔄 Drug Interactions:\u003cbr\u003e•    Diuretics:\u003cbr\u003eMay increase risk of volume depletion; monitor renal function and hydration\u003cbr\u003e•    1,5-Anhydroglucitol (1,5-AG) Assay:\u003cbr\u003eNot reliable in patients on SGLT2 inhibitors; use alternative glycemic monitoring\u003cbr\u003e•    Strong P-gp\/CYP3A4 Inducers (e.g., Rifampin):\u003cbr\u003eMay reduce Linagliptin efficacy — alternative therapies recommended\u003cbr\u003e________________________________________\u003cbr\u003e🩺 Indications:\u003cbr\u003e•    Adjunct to diet and exercise in adults with type 2 diabetes mellitus, when:\u003cbr\u003eo    Monotherapy with either agent is insufficient\u003cbr\u003eo    Metformin and\/or sulfonylurea are inadequate\u003cbr\u003eo    Patient is already being treated with free combination of both drugs\u003cbr\u003e•    Empagliflozin also indicated to reduce risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e❌ When Not to Use:\u003cbr\u003eDo not use if the patient has:\u003cbr\u003e•    Hypersensitivity to Empagliflozin, Linagliptin, or excipients\u003cbr\u003e•    Known allergy to SGLT2 inhibitors or DPP-4 inhibitors\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Precautions:\u003cbr\u003e•    Risk of acute pancreatitis with DPP-4 inhibitors, including Linagliptin\u003cbr\u003e•    Discontinue immediately if pancreatitis is suspected\u003cbr\u003e•    Avoid restarting if confirmed\u003cbr\u003e•    Use caution in patients with history of pancreatitis\u003cbr\u003e________________________________________\u003cbr\u003e🚨 Warnings:\u003cbr\u003eWarning 1:\u003cbr\u003e•    Use caution in patients at risk of hypotension\u003cbr\u003eo    Especially those with CVD, on anti-hypertensives, or age ≥75\u003cbr\u003eWarning 2:\u003cbr\u003e•    Increased risk of lower limb amputations, particularly toes\u003cbr\u003eo    Advise patients on preventative foot care\u003cbr\u003eWarning 3:\u003cbr\u003e•    Risk of urinary tract infections\u003cbr\u003eo    Monitor for symptoms and treat promptly if infection is suspected\u003cbr\u003e________________________________________\u003cbr\u003e🤰 Pregnancy Category:\u003cbr\u003eAlways consult your physician before using during pregnancy or breastfeeding.\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e🏠 Storage:\u003cbr\u003eYes – Store at room temperature, away from direct light and heat\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53319073071435,"sku":null,"price":375.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/images_12.jpg?v=1757059256","url":"https:\/\/wellnesspharmacy.pk\/products\/diampa-lt-tablets-25mg-5mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}