{"product_id":"diampa-m-tablets-5mg-1000mg","title":"Diampa-M Tablets 5mg\/1000mg","description":"\u003cp\u003eMedicine Name: Diampa-M Tablets 5mg\/1000mg\u003c\/p\u003e\n\u003cp\u003e💊 Diampa-M Tablets – Product Specification Sheet\u003cbr\u003e________________________________________\u003cbr\u003e✅ Requires Prescription\u003cbr\u003eYes\u003cbr\u003e________________________________________\u003cbr\u003e🧪 Generic Composition\u003cbr\u003e•    Empagliflozin\u003cbr\u003e•    Metformin Hydrochloride (HCl)\u003cbr\u003e________________________________________\u003cbr\u003e🩺 Used For\u003cbr\u003eManagement of Type 2 Diabetes Mellitus as an adjunct to diet and exercise.\u003cbr\u003e________________________________________\u003cbr\u003e⚙️ Mechanism of Action\u003cbr\u003eMetformin HCl (Biguanide):\u003cbr\u003e•    Lowers both fasting and post-meal blood glucose levels\u003cbr\u003e•    Decreases hepatic glucose production\u003cbr\u003e•    Reduces intestinal glucose absorption\u003cbr\u003e•    Improves insulin sensitivity and glucose uptake in peripheral tissues\u003cbr\u003eEmpagliflozin (SGLT2 Inhibitor):\u003cbr\u003e•    Inhibits sodium-glucose co-transporter 2 in the kidney\u003cbr\u003e•    Reduces renal reabsorption of glucose\u003cbr\u003e•    Increases urinary glucose excretion\u003cbr\u003e•    Lowers blood glucose independent of insulin pathway\u003cbr\u003e________________________________________\u003cbr\u003e📦 Dosage\u003cbr\u003eEmpagliflozin + Metformin HCl\u003cbr\u003e(Individualized as per physician’s advice based on renal function, prior therapy, and patient response.)\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Side Effects\u003cbr\u003eEmpagliflozin-related (≥5%):\u003cbr\u003e•    Urinary tract infections\u003cbr\u003e•    Female genital mycotic infections\u003cbr\u003eMetformin-related (\u0026gt;5%):\u003cbr\u003e•    Diarrhea\u003cbr\u003e•    Nausea \/ Vomiting\u003cbr\u003e•    Flatulence\u003cbr\u003e•    Abdominal discomfort\u003cbr\u003e•    Indigestion\u003cbr\u003e•    Asthenia (weakness)\u003cbr\u003e•    Headache\u003cbr\u003e________________________________________\u003cbr\u003e🔄 Drug Interactions\u003cbr\u003e•    Diuretics → Risk of volume depletion\u003cbr\u003e•    Positive urine glucose test → Due to glycosuria\u003cbr\u003e•    1,5-anhydroglucitol (1,5-AG) assay → Unreliable glycemic monitoring\u003cbr\u003e•    Cimetidine, ranolazine, dolutegravir, vandetanib → May affect metformin levels\u003cbr\u003e•    Zonisamide, acetazolamide, corticosteroids → Risk of lactic acidosis\u003cbr\u003e•    Estrogens, phenytoin, calcium channel blockers, oral contraceptives, etc. → May reduce glycemic control\u003cbr\u003e________________________________________\u003cbr\u003e🎯 Indication\u003cbr\u003e•    For adult patients with Type 2 Diabetes Mellitus who:\u003cbr\u003eo    Are inadequately controlled with either empagliflozin or metformin alone\u003cbr\u003eo    Are already treated with empagliflozin + metformin separately\u003cbr\u003e•    Used to improve glycemic control\u003cbr\u003e•    Not indicated for Type 1 Diabetes\u003cbr\u003e________________________________________\u003cbr\u003e🚫 Contraindications (When Not to Use)\u003cbr\u003e•    Renal impairment or end-stage renal disease (ESRD), including patients on dialysis\u003cbr\u003e•    Metabolic acidosis, including diabetic ketoacidosis\u003cbr\u003e•    Hypersensitivity to empagliflozin or metformin\u003cbr\u003e________________________________________\u003cbr\u003e🛑 Warnings\u003cbr\u003e1.    Lactic Acidosis (Metformin-related):\u003cbr\u003eo    Rare, but serious and potentially fatal\u003cbr\u003eo    Early symptoms: Malaise, myalgia, abdominal pain, respiratory distress\u003cbr\u003eo    Risk factors: Renal impairment, dehydration, alcohol abuse\u003cbr\u003e2.    Hypotension (Empagliflozin-related):\u003cbr\u003eo    Due to intravascular volume contraction\u003cbr\u003eo    Common in elderly, renally impaired, or diuretic users\u003cbr\u003eo    Monitor blood pressure and hydration status\u003cbr\u003e3.    Ketoacidosis (Empagliflozin-related):\u003cbr\u003eo    Potentially life-threatening\u003cbr\u003eo    Symptoms: Nausea, vomiting, abdominal pain, labored breathing\u003cbr\u003eo    Discontinue if suspected; not for use in type 1 diabetes\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Precaution\u003cbr\u003e•    Store out of children's reach\u003cbr\u003e•    Maintain in a cool, dry place, protected from light and heat\u003cbr\u003e________________________________________\u003cbr\u003e🤰 Pregnancy Category\u003cbr\u003e•    Use only under physician supervision during pregnancy or lactation\u003cbr\u003e________________________________________\u003cbr\u003e🧊 Storage Required\u003cbr\u003eYes — Store at room temperature, away from direct light and moisture\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53319321420107,"sku":null,"price":440.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/21937.webp?v=1757060444","url":"https:\/\/wellnesspharmacy.pk\/products\/diampa-m-tablets-5mg-1000mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}