{"product_id":"dioplus-tablets-5-160mg","title":"Dioplus Tablets 5\/160mg","description":"\u003cp\u003eMedicine Name: Dioplus Tablets 5\/160mg\u003cbr\u003e💊 Dioplus Tablets – Product Specification\u003cbr\u003e________________________________________\u003cbr\u003e✅ Requires Prescription:\u003cbr\u003eYes\u003cbr\u003e________________________________________\u003cbr\u003e🧪 Generics:\u003cbr\u003eAmlodipine Besilate + Valsartan\u003cbr\u003e________________________________________\u003cbr\u003e🎯 Used For:\u003cbr\u003e•    Management of Hypertension (High Blood Pressure)\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e⚙️ How It Works:\u003cbr\u003e•    Amlodipine is a calcium channel blocker that dilates blood vessels and improves blood flow.\u003cbr\u003e•    Valsartan is an angiotensin II receptor blocker (ARB) that prevents vasoconstriction.\u003cbr\u003e•    The combination of both drugs offers additive antihypertensive effects, controlling blood pressure more effectively than either alone.\u003cbr\u003e________________________________________\u003cbr\u003e💊 Dosage:\u003cbr\u003e•    Contains Amlodipine Besilate + Valsartan\u003cbr\u003e(Use as prescribed by a healthcare professional.)\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Side Effects:\u003cbr\u003e•    Common:\u003cbr\u003eo    Nasopharyngitis, influenza\u003cbr\u003eo    Headache, fatigue, asthenia\u003cbr\u003eo    Facial and peripheral edema, flushing, hot flushes\u003cbr\u003eo    Dizziness (including postural), somnolence, visual disturbances\u003cbr\u003eo    Hypokalemia, hyponatremia, hyperuricemia\u003cbr\u003e•    Gastrointestinal:\u003cbr\u003eo    Abdominal discomfort, upper abdominal pain\u003cbr\u003eo    Constipation, diarrhea, dry mouth, nausea\u003cbr\u003e•    Musculoskeletal and Others:\u003cbr\u003eo    Arthralgia, back pain, joint swelling\u003cbr\u003eo    Paraesthesia, rash, erythema\u003cbr\u003e•    Cardiovascular:\u003cbr\u003eo    Palpitations, tachycardia, orthostatic hypotension\u003cbr\u003e________________________________________\u003cbr\u003e🔄 Drug Interactions:\u003cbr\u003e•    CYP3A4 inhibitors (e.g. protease inhibitors, azole antifungals, erythromycin, verapamil)\u003cbr\u003e•    CYP3A4 inducers (e.g. rifampicin, St. John’s Wort)\u003cbr\u003e•    Simvastatin, Sildenafil, Lithium\u003cbr\u003e•    NSAIDs, potassium-sparing diuretics, potassium supplements\u003cbr\u003e•    Grapefruit juice (increases amlodipine levels)\u003cbr\u003e•    Other antihypertensives — additive effect\u003cbr\u003e________________________________________\u003cbr\u003e💡 Indication:\u003cbr\u003e•    Indicated for the treatment of essential hypertension in patients where combination therapy is appropriate.\u003cbr\u003e________________________________________\u003cbr\u003e🚫 When Not to Use:\u003cbr\u003e•    Hypersensitivity to amlodipine, valsartan, dihydropyridine derivatives, or any excipient\u003cbr\u003e•    Severe hepatic impairment, biliary cirrhosis, or cholestasis\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Precautions:\u003cbr\u003e•    Use cautiously in patients with renal artery stenosis (unilateral\/bilateral or in a solitary kidney) as it may cause elevated blood urea and creatinine levels.\u003cbr\u003e________________________________________\u003cbr\u003e🚨 Warnings:\u003cbr\u003eWarning 1:\u003cbr\u003e•    Use with potassium-sparing diuretics, potassium supplements, or salt substitutes containing potassium may lead to hyperkalemia. Monitor potassium levels closely.\u003cbr\u003eWarning 2:\u003cbr\u003e•    Not recommended in cases of hypertensive crisis — safety and efficacy not established.\u003cbr\u003eWarning 3:\u003cbr\u003e•    Angioedema (swelling of face, lips, tongue, or throat) may occur. If this develops, discontinue immediately and do not re-administer.\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e🤰 Pregnancy Category:\u003cbr\u003e•    Always consult your physician before using this medicine. Use during pregnancy is not recommended.\u003cbr\u003e________________________________________\u003cbr\u003e🏠 Storage:\u003cbr\u003e✅ Yes – Store at room temperature, protected from direct light and heat. \u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53318868599115,"sku":null,"price":565.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_6843.jpg?v=1757057803","url":"https:\/\/wellnesspharmacy.pk\/products\/dioplus-tablets-5-160mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}