{"product_id":"dioplus-tablets-5-80mg","title":"Dioplus Tablets 5\/80mg","description":"\u003cp\u003eMedicine Name: Dioplus Tablets 5\/80mg\u003c\/p\u003e\n\u003cp\u003e💊 Dioplus Tablets – Product Specification\u003cbr\u003e________________________________________\u003cbr\u003e📋 Requires Prescription:\u003cbr\u003e✅ Yes\u003cbr\u003e________________________________________\u003cbr\u003e🧪 Generics:\u003cbr\u003eAmlodipine Besilate + Valsartan\u003cbr\u003e________________________________________\u003cbr\u003e🎯 Used For:\u003cbr\u003e•    Hypertension (High Blood Pressure)\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e⚙️ How It Works:\u003cbr\u003e•    Amlodipine is a calcium channel blocker that relaxes blood vessels and improves blood flow.\u003cbr\u003e•    Valsartan is an angiotensin II receptor blocker (ARB) that prevents blood vessels from narrowing.\u003cbr\u003e•    Together, they have complementary mechanisms and a stronger blood pressure–lowering effect than when used alone.\u003cbr\u003e________________________________________\u003cbr\u003e💊 Dosage:\u003cbr\u003e•    Amlodipine Besilate + Valsartan\u003cbr\u003e(Use as prescribed by a healthcare professional.)\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Side Effects:\u003cbr\u003e•    Common:\u003cbr\u003eo    Nasopharyngitis, influenza\u003cbr\u003eo    Hypokalemia, headache, fatigue, asthenia\u003cbr\u003eo    Facial edema, peripheral edema, flushing, hot flushes, pitting edema\u003cbr\u003eo    Abdominal discomfort, constipation, diarrhea, nausea, dry mouth\u003cbr\u003e•    Uncommon to Rare:\u003cbr\u003eo    Visual impairment, dizziness (including postural), paraesthesia, somnolence\u003cbr\u003eo    Palpitations, tachycardia, orthostatic hypotension\u003cbr\u003eo    Back pain, joint swelling, arthralgia\u003cbr\u003eo    Rash, erythema\u003cbr\u003e•    Metabolic:\u003cbr\u003eo    Hypercalcemia, hyperlipidemia, hyperuricemia, hyponatremia\u003cbr\u003eo    Anorexia\u003cbr\u003e________________________________________\u003cbr\u003e🔄 Drug Interactions:\u003cbr\u003e•    CYP3A4 inhibitors: Protease inhibitors, azole antifungals, macrolides (e.g. erythromycin, clarithromycin), verapamil, diltiazem\u003cbr\u003e•    CYP3A4 inducers: Rifampicin, St. John’s Wort (Hypericum perforatum)\u003cbr\u003e•    Others:\u003cbr\u003eo    Simvastatin\u003cbr\u003eo    NSAIDs\u003cbr\u003eo    Lithium\u003cbr\u003eo    Sildenafil\u003cbr\u003eo    Potassium supplements or potassium-sparing diuretics\u003cbr\u003eo    Grapefruit juice (increases amlodipine levels)\u003cbr\u003e________________________________________\u003cbr\u003e💡 Indication:\u003cbr\u003e•    Treatment of essential hypertension (high blood pressure not caused by another condition).\u003cbr\u003e________________________________________\u003cbr\u003e❌ When Not to Use:\u003cbr\u003e•    Known hypersensitivity to amlodipine, valsartan, or any excipients\u003cbr\u003e•    Severe hepatic impairment, biliary cirrhosis, or cholestasis\u003cbr\u003e•    Allergy to dihydropyridine derivatives\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Precautions:\u003cbr\u003e•    Use cautiously in patients with renal artery stenosis, as blood urea and creatinine levels may rise.\u003cbr\u003e•    Monitor kidney function and electrolytes in at-risk patients.\u003cbr\u003e________________________________________\u003cbr\u003e🚨 Warnings:\u003cbr\u003eWarning 1:\u003cbr\u003e•    Risk of hyperkalemia when used with potassium supplements, potassium-sparing diuretics, or potassium-containing salt substitutes. Monitor potassium levels closely.\u003cbr\u003eWarning 2:\u003cbr\u003e•    Not recommended for use in hypertensive crisis as safety and efficacy are unproven.\u003cbr\u003eWarning 3:\u003cbr\u003e•    Angioedema (face, lips, tongue, throat swelling) may occur. Stop immediately if symptoms develop. Do not restart therapy in affected patients.\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e👶 Pregnancy Category:\u003cbr\u003e•    Consult your doctor before use. Not recommended during pregnancy.\u003cbr\u003e________________________________________\u003cbr\u003e🏠 Storage:\u003cbr\u003e✅ Yes — Store at room temperature, away from direct sunlight and heat.\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53318822003019,"sku":null,"price":430.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_6845.jpg?v=1757057462","url":"https:\/\/wellnesspharmacy.pk\/products\/dioplus-tablets-5-80mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}