{"product_id":"duragesic-tablets-35mg-450mg","title":"Duragesic Tablets 35mg\/450mg","description":"\u003cp\u003eMedicine Name: Duragesic Tablets 35mg\/450mg\u003c\/p\u003e\n\u003cp\u003e💊 Duragesic Tablets – Product Specification Sheet\u003cbr\u003e________________________________________\u003cbr\u003e✅ Requires Prescription\u003cbr\u003eYes\u003cbr\u003e________________________________________\u003cbr\u003e🧪 Generic Composition\u003cbr\u003e•    Paracetamol\u003cbr\u003e•    Orphenadrine Citrate\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e🩺 Used For\u003cbr\u003eMuscle Relaxant\u003cbr\u003eRelief of pain and discomfort associated with muscle spasms, tension headaches, traumatic musculoskeletal conditions, and spasmodic conditions of the head, neck, limbs, and trunk.\u003cbr\u003e________________________________________\u003cbr\u003e⚙️ Mechanism of Action\u003cbr\u003e•    Orphenadrine Citrate:\u003cbr\u003eA centrally acting skeletal muscle relaxant with mild anticholinergic properties. It works by relieving muscle spasms and associated pain.\u003cbr\u003e•    Paracetamol (Acetaminophen):\u003cbr\u003eAn analgesic and antipyretic that helps reduce pain and fever by inhibiting prostaglandin synthesis in the central nervous system.\u003cbr\u003e________________________________________\u003cbr\u003e📦 Dosage\u003cbr\u003eParacetamol + Orphenadrine Citrate\u003cbr\u003e(Use as directed by the physician. Dosage may vary depending on the condition and patient response.)\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Side Effects\u003cbr\u003eOrphenadrine Citrate\u003cbr\u003e•    Common: Dry mouth, blurred vision, drowsiness, dizziness, headache, tachycardia, palpitations, nausea, constipation, urinary retention\u003cbr\u003e•    Less Common: Skin rash, sedation, allergic reactions, mental confusion (especially in the elderly)\u003cbr\u003e•    Rare: Aplastic anemia (very rare)\u003cbr\u003eParacetamol\u003cbr\u003e•    Generally well tolerated\u003cbr\u003e•    Possible reactions: Nausea, dyspepsia, allergic reactions, and rare hematological disturbances\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e🔄 Drug Interactions\u003cbr\u003e•    Phenothiazines\u003cbr\u003e•    Metoclopramide\u003cbr\u003e•    Anticholinergic agents (e.g. propantheline, tricyclic antidepressants, narcotics)\u003cbr\u003e•    Alcohol and anticonvulsants (may increase risk of liver damage with paracetamol)\u003cbr\u003e•    Other medicines containing paracetamol or orphenadrine — avoid concurrent use\u003cbr\u003e________________________________________\u003cbr\u003e🎯 Indications\u003cbr\u003e•    Tension headaches and occipital headaches with skeletal muscle spasm\u003cbr\u003e•    Acute musculoskeletal conditions such as:\u003cbr\u003eo    Sprains and strains\u003cbr\u003eo    Whiplash injuries\u003cbr\u003eo    Acute torticollis\u003cbr\u003eo    Prolapsed intervertebral disc\u003cbr\u003e________________________________________\u003cbr\u003e🚫 Contraindications (When Not to Use)\u003cbr\u003e•    Glaucoma\u003cbr\u003e•    Prostatic hypertrophy or bladder neck obstruction\u003cbr\u003e•    Myasthenia gravis\u003cbr\u003e•    Oesophageal spasm or pyloric\/duodenal obstruction\u003cbr\u003e•    Hypersensitivity to paracetamol or orphenadrine citrate\u003cbr\u003e________________________________________\u003cbr\u003e🛑 Warnings\u003cbr\u003e1.    Cardiac Conditions (Orphenadrine):\u003cbr\u003eUse with caution in patients with tachycardia, heart failure, coronary artery disease, or arrhythmias.\u003cbr\u003e2.    Hepatic\/Renal Impairment (Paracetamol):\u003cbr\u003eCaution in patients with liver or kidney dysfunction. Risk of hepatotoxicity with overdose or prolonged use.\u003cbr\u003e3.    Long-term Use (Orphenadrine):\u003cbr\u003eLong-term safety not established. Periodic monitoring of liver function, urine, and blood tests is advised for prolonged therapy.\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e⚠️ Precaution\u003cbr\u003eAvoid concurrent use of other medicines containing paracetamol or orphenadrine to prevent overdose or adverse effects.\u003cbr\u003e________________________________________\u003cbr\u003e🤰 Pregnancy Category\u003cbr\u003eAlways consult a physician before use during pregnancy or breastfeeding.\u003cbr\u003e________________________________________\u003cbr\u003e🧊 Storage\u003cbr\u003eYes — Store at room temperature, away from heat, moisture, and direct light.\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53319343571275,"sku":null,"price":455.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/DURAGESIC_TAB__1.webp?v=1757060811","url":"https:\/\/wellnesspharmacy.pk\/products\/duragesic-tablets-35mg-450mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}