{"product_id":"empaa-l-tablets-10mg-5mg","title":"Empaa-L Tablets 10mg\/5mg","description":"\u003cp\u003eMedicine Name: Empaa-L Tablets 10mg\/5mg\u003c\/p\u003e\n\u003cp\u003eEmpaa-L Tablets Specification\u003cbr\u003eRequires Prescription:\u003cbr\u003eYes\u003cbr\u003e________________________________________\u003cbr\u003eGenerics:\u003cbr\u003eEmpagliflozin + Linagliptin\u003cbr\u003e________________________________________\u003cbr\u003eUsed For:\u003cbr\u003eType 2 Diabetes Mellitus\u003cbr\u003eAs an adjunct to diet and exercise to improve glycemic control\u003cbr\u003eFor patients inadequately controlled on metformin, sulfonylurea, or monotherapy of either component\u003cbr\u003eEmpagliflozin additionally indicated to reduce cardiovascular death in adults with established cardiovascular disease\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003eHow It Works:\u003cbr\u003eEmpagliflozin is an SGLT2 inhibitor that reduces renal glucose reabsorption, increasing urinary glucose excretion to lower blood sugar.\u003cbr\u003eLinagliptin is a DPP-4 inhibitor that increases the levels of active incretin hormones (GLP-1 and GIP), enhancing glucose-dependent insulin release and decreasing glucagon levels, contributing to overall glycemic control.\u003cbr\u003e________________________________________\u003cbr\u003eEmpaa-L Tablets Usage and Safety\u003cbr\u003eDosage:\u003cbr\u003eEmpagliflozin + Linagliptin\u003cbr\u003eTaken once daily; dosage depends on individual treatment needs and medical condition.\u003cbr\u003e________________________________________\u003cbr\u003eSide Effects:\u003cbr\u003eCommon:\u003cbr\u003eUrinary tract infections (including pyelonephritis, urosepsis)\u003cbr\u003eGenital infections (vaginal moniliasis, balanitis, vulvovaginitis)\u003cbr\u003eNasopharyngitis\u003cbr\u003eHypoglycemia (when used with insulin or sulfonylureas)\u003cbr\u003eIncreased urination, thirst, rash, cough, pruritus\u003cbr\u003eElevated amylase and lipase\u003cbr\u003eUncommon:\u003cbr\u003eHypersensitivity reactions (e.g., angioedema, urticaria)\u003cbr\u003ePancreatitis\u003cbr\u003eVolume depletion\u003cbr\u003eElevated hematocrit, blood lipids, or serum creatinine\u003cbr\u003eDysuria\u003cbr\u003eRare \/ Not Known:\u003cbr\u003eNecrotizing fasciitis of the perineum (Fournier’s gangrene)\u003cbr\u003eBullous pemphigoid\u003cbr\u003e________________________________________\u003cbr\u003eDrug Interactions:\u003cbr\u003eDiuretics (e.g., thiazides, loop diuretics): Increased risk of dehydration or hypotension\u003cbr\u003e1,5-anhydroglucitol (1,5-AG): Not a reliable glycemic marker in SGLT2 users\u003cbr\u003eCYP3A4\/P-gp inducers (e.g., Rifampin): May reduce linagliptin efficacy; consider alternatives\u003cbr\u003e________________________________________\u003cbr\u003eIndications:\u003cbr\u003eFor adults with type 2 diabetes mellitus:\u003cbr\u003eWhen monotherapy (or dual therapy with metformin or sulfonylureas) is insufficient\u003cbr\u003eFor patients already stabilized on both components as separate tablets\u003cbr\u003eEmpagliflozin is also indicated to reduce cardiovascular mortality in those with established CV disease\u003cbr\u003e________________________________________\u003cbr\u003eWhen Not to Use:\u003cbr\u003eKnown hypersensitivity to Empagliflozin, Linagliptin, other SGLT2\/DPP-4 inhibitors, or product excipients\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eEmpaa-L Tablets Precautions \u0026amp; Warnings\u003cbr\u003ePrecaution:\u003cbr\u003eRisk of acute pancreatitis with DPP-4 inhibitors. Discontinue immediately if pancreatitis is suspected or confirmed. Avoid re-initiation in such patients.\u003cbr\u003e________________________________________\u003cbr\u003eWarnings:\u003cbr\u003e1. Hypotension Risk:\u003cbr\u003eEmpagliflozin may cause a drop in blood pressure; use with caution in elderly patients, those on antihypertensives, or those with cardiovascular disease.\u003cbr\u003e2. Risk of Lower Limb Amputation:\u003cbr\u003eIncreased incidence reported. Encourage patients to maintain good foot care and monitor regularly.\u003cbr\u003e3. Urinary Tract Infections:\u003cbr\u003eSGLT2 inhibitors increase UTI risk. Monitor and treat promptly if symptoms appear.\u003cbr\u003e________________________________________\u003cbr\u003ePregnancy Category:\u003cbr\u003eAlways consult a physician before use during pregnancy or breastfeeding.\u003cbr\u003e________________________________________\u003cbr\u003eStorage:\u003cbr\u003eStore at room temperature, protected from direct light and heat\u003cbr\u003eKeep out of reach of children\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53336090181963,"sku":null,"price":840.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/images_17.jpg?v=1757312382","url":"https:\/\/wellnesspharmacy.pk\/products\/empaa-l-tablets-10mg-5mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}