{"product_id":"empaa-m-tablets-12-5-500mg","title":"Empaa-M Tablets 12.5\/500mg","description":"\u003cp\u003eMedicine Name: Empaa-M Tablets 12.5\/500mg\u003c\/p\u003e\n\u003cp\u003eEmpaa-M Tablets Specification\u003cbr\u003eRequires Prescription\u003cbr\u003eYes\u003cbr\u003e________________________________________\u003cbr\u003eGenerics\u003cbr\u003eEmpagliflozin\u003cbr\u003eMetformin Hydrochloride (HCl)\u003cbr\u003e________________________________________\u003cbr\u003eUsed For\u003cbr\u003eManagement of Type 2 Diabetes Mellitus\u003cbr\u003e(as an adjunct to diet and exercise)\u003cbr\u003e________________________________________\u003cbr\u003eHow It Works\u003cbr\u003eMetformin HCl:\u003cbr\u003eAn antihyperglycemic agent that:\u003cbr\u003eDecreases hepatic glucose production\u003cbr\u003eDecreases intestinal glucose absorption\u003cbr\u003eImproves insulin sensitivity by enhancing peripheral glucose uptake and utilization\u003cbr\u003eEmpagliflozin:\u003cbr\u003eAn SGLT2 inhibitor that:\u003cbr\u003eReduces renal glucose reabsorption\u003cbr\u003eLowers the renal threshold for glucose\u003cbr\u003eIncreases urinary glucose excretion\u003cbr\u003e________________________________________\u003cbr\u003eDosage\u003cbr\u003eCombination of Empagliflozin and Metformin HCl\u003cbr\u003eDosage to be determined by a healthcare provider based on patient’s medical condition\u003cbr\u003e________________________________________\u003cbr\u003eSide Effects\u003cbr\u003eEmpagliflozin (≥5% incidence):\u003cbr\u003eUrinary tract infections\u003cbr\u003eFemale genital mycotic infections\u003cbr\u003eMetformin (\u0026gt;5% incidence):\u003cbr\u003eDiarrhea\u003cbr\u003eNausea\/Vomiting\u003cbr\u003eFlatulence\u003cbr\u003eAbdominal discomfort\u003cbr\u003eIndigestion\u003cbr\u003eAsthenia (weakness)\u003cbr\u003eHeadache\u003cbr\u003e________________________________________\u003cbr\u003eDrug Interactions\u003cbr\u003eDiuretics\u003cbr\u003eRanolazine, Vandetanib, Dolutegravir, Cimetidine\u003cbr\u003eZonisamide, Acetazolamide, Dichlorphenamide\u003cbr\u003eCorticosteroids, Phenothiazines, Thyroid products, Estrogens, Oral contraceptives\u003cbr\u003ePhenytoin, Nicotinic acid, Sympathomimetics, Calcium channel blockers, Isoniazid\u003cbr\u003eNifedipine\u003cbr\u003eMay affect urine glucose tests and 1,5-anhydroglucitol (1,5-AG) assays\u003cbr\u003e________________________________________\u003cbr\u003eIndication\u003cbr\u003eFor adults with Type 2 Diabetes Mellitus:\u003cbr\u003eNot adequately controlled with either empagliflozin or metformin alone\u003cbr\u003eAlready being treated with both agents\u003cbr\u003e________________________________________\u003cbr\u003eWhen Not to Use\u003cbr\u003eDo not use in cases of:\u003cbr\u003eRenal Impairment, ESRD, or patients on dialysis\u003cbr\u003eMetabolic acidosis, including diabetic ketoacidosis\u003cbr\u003eHistory of serious hypersensitivity to empagliflozin or metformin\u003cbr\u003e________________________________________\u003cbr\u003ePrecautions\u003cbr\u003eKeep out of reach of children\u003cbr\u003eStore in a cool, dry place, away from direct heat and light\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eWarnings\u003cbr\u003eLactic Acidosis\u003cbr\u003eRare but potentially fatal\u003cbr\u003eNonspecific symptoms: malaise, myalgia, abdominal pain, drowsiness\u003cbr\u003eCan lead to hypothermia, hypotension, bradyarrhythmias\u003cbr\u003eHypotension\u003cbr\u003eDue to volume depletion from empagliflozin\u003cbr\u003eMonitor in patients with renal impairment, elderly, or those on diuretics\u003cbr\u003eAssess and correct fluid status before initiating\u003cbr\u003eKetoacidosis\u003cbr\u003eSerious condition, requires hospitalization\u003cbr\u003eCan occur even in type 2 diabetics\u003cbr\u003eNot for use in type 1 diabetes mellitus\u003cbr\u003e________________________________________\u003cbr\u003ePregnancy Category\u003cbr\u003eConsult a healthcare provider before use\u003cbr\u003e________________________________________\u003cbr\u003eStorage (YES\/NO)\u003cbr\u003eYes — Store at room temperature, protected from light and heat\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53336094212427,"sku":null,"price":260.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/images_18.jpg?v=1757312621","url":"https:\/\/wellnesspharmacy.pk\/products\/empaa-m-tablets-12-5-500mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}