{"product_id":"empaa-m-xr-tablets-12-5-1000mg","title":"Empaa-M Xr Tablets 12.5\/1000mg","description":"\u003cp\u003eMedicine Name: Empaa-M Xr Tablets 12.5\/1000mg\u003c\/p\u003e\n\u003cp\u003eEmpaa-M XR Tablets Specification\u003cbr\u003eRequires Prescription\u003cbr\u003eYes\u003cbr\u003e________________________________________\u003cbr\u003eGenerics\u003cbr\u003eEmpagliflozin\u003cbr\u003eMetformin Hydrochloride (HCl) – Extended Release (XR)\u003cbr\u003e________________________________________\u003cbr\u003eUsed For\u003cbr\u003eTreatment of Type 2 Diabetes Mellitus\u003cbr\u003e(Adjunct to diet and exercise)\u003cbr\u003e________________________________________\u003cbr\u003eHow It Works\u003cbr\u003eMetformin HCl (Extended Release):\u003cbr\u003eImproves glucose tolerance by:\u003cbr\u003eDecreasing liver glucose production\u003cbr\u003eReducing intestinal glucose absorption\u003cbr\u003eEnhancing insulin sensitivity and peripheral glucose uptake\u003cbr\u003eEmpagliflozin:\u003cbr\u003eAn SGLT2 inhibitor that:\u003cbr\u003eLowers renal threshold for glucose\u003cbr\u003eIncreases glucose excretion via urine\u003cbr\u003eReduces blood glucose levels\u003cbr\u003e________________________________________\u003cbr\u003eDosage\u003cbr\u003eCombination of Empagliflozin and Metformin HCl XR\u003cbr\u003eIndividualized based on patient’s clinical response and tolerability\u003cbr\u003eTo be taken once daily with food to reduce gastrointestinal side effects\u003cbr\u003e________________________________________\u003cbr\u003eSide Effects\u003cbr\u003eEmpagliflozin (≥5%):\u003cbr\u003eUrinary tract infections\u003cbr\u003eFemale genital mycotic infections\u003cbr\u003eMetformin XR (\u0026gt;5%):\u003cbr\u003eDiarrhea\u003cbr\u003eNausea\/Vomiting\u003cbr\u003eFlatulence\u003cbr\u003eAbdominal discomfort\u003cbr\u003eIndigestion\u003cbr\u003eAsthenia (fatigue)\u003cbr\u003eHeadache\u003cbr\u003e________________________________________\u003cbr\u003eDrug Interactions\u003cbr\u003eDiuretics\u003cbr\u003eRanolazine, Vandetanib, Dolutegravir, Cimetidine\u003cbr\u003eZonisamide, Acetazolamide, Dichlorphenamide\u003cbr\u003eCorticosteroids, Phenothiazines, Thyroid products, Estrogens, Oral contraceptives\u003cbr\u003ePhenytoin, Nicotinic acid, Sympathomimetics, Calcium channel blockers, Isoniazid\u003cbr\u003eNifedipine\u003cbr\u003eMay cause false-positive urine glucose tests\u003cbr\u003eMay interfere with 1,5-anhydroglucitol (1,5-AG) assays\u003cbr\u003e________________________________________\u003cbr\u003eIndication\u003cbr\u003eIndicated as an adjunct to diet and exercise to:\u003cbr\u003eImprove glycemic control in adults with type 2 diabetes mellitus\u003cbr\u003eFor patients not adequately controlled on either empagliflozin or metformin alone\u003cbr\u003eFor those already receiving both agents in separate formulations\u003cbr\u003e________________________________________\u003cbr\u003eWhen Not to Use\u003cbr\u003eAvoid in patients with:\u003cbr\u003eSevere renal impairment, end-stage renal disease (ESRD), or on dialysis\u003cbr\u003eMetabolic acidosis, including diabetic ketoacidosis\u003cbr\u003eHistory of serious hypersensitivity to empagliflozin or metformin\u003cbr\u003e________________________________________\u003cbr\u003ePrecautions\u003cbr\u003eKeep out of reach of children\u003cbr\u003eStore in a cool, dry place, protected from direct heat and light\u003cbr\u003e________________________________________\u003cbr\u003eWarnings\u003cbr\u003e1. Lactic Acidosis\u003cbr\u003eA rare but potentially fatal complication\u003cbr\u003eWatch for symptoms like malaise, muscle pain, breathing difficulty, drowsiness\u003cbr\u003eOften occurs in cases of renal dysfunction or dehydration\u003cbr\u003e2. Hypotension\u003cbr\u003eDue to volume depletion from empagliflozin\u003cbr\u003eMonitor in elderly, renal-impaired, or patients on diuretics\u003cbr\u003eAssess and correct volume status before starting\u003cbr\u003e3. Ketoacidosis\u003cbr\u003eRare but life-threatening, may occur even in type 2 diabetes\u003cbr\u003eSymptoms include nausea, vomiting, abdominal pain, confusion, and unusual fatigue\u003cbr\u003eNot to be used for type 1 diabetes\u003cbr\u003e________________________________________\u003cbr\u003ePregnancy Category\u003cbr\u003eAlways consult a physician prior to use during pregnancy or breastfeeding\u003cbr\u003e________________________________________\u003cbr\u003eStorage (YES\/NO)\u003cbr\u003eYes — Store at room temperature, away from light and heat\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53336095916363,"sku":null,"price":550.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/images_19.jpg?v=1757312799","url":"https:\/\/wellnesspharmacy.pk\/products\/empaa-m-xr-tablets-12-5-1000mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}