{"product_id":"empagen-m-xr-tablets-12-5-1000mg","title":"Empagen-M Xr Tablets 12.5\/1000mg","description":"\u003cp\u003eMedicine Name: Empagen-M Xr Tablets 12.5\/1000mg\u003c\/p\u003e\n\u003cp\u003e🩺 Empagen-M XR Tablets – Product Specification\u003cbr\u003e________________________________________\u003cbr\u003e📌 Requires Prescription:\u003cbr\u003e✅ Yes\u003cbr\u003e________________________________________\u003cbr\u003e💊 Generics (Active Ingredients):\u003cbr\u003eEmpagliflozin (SGLT2 inhibitor)\u003cbr\u003eMetformin Hydrochloride (XR) (Biguanide class)\u003cbr\u003e________________________________________\u003cbr\u003e🧪 Used For:\u003cbr\u003eManagement of Type 2 Diabetes Mellitus (T2DM) in adults\u003cbr\u003eFor patients not adequately controlled with metformin or empagliflozin alone\u003cbr\u003eFor patients already stabilized on both agents\u003cbr\u003e________________________________________\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e⚙️ How It Works:\u003cbr\u003eMetformin:\u003cbr\u003eDecreases hepatic glucose production\u003cbr\u003eReduces intestinal glucose absorption\u003cbr\u003eImproves insulin sensitivity and glucose uptake\u003cbr\u003eDoes not cause hypoglycemia or hyperinsulinemia\u003cbr\u003eEmpagliflozin:\u003cbr\u003eInhibits SGLT2 → ↓ glucose reabsorption in kidneys\u003cbr\u003e↑ urinary glucose excretion → ↓ blood glucose levels\u003cbr\u003e________________________________________\u003cbr\u003e💊 Dosage Form:\u003cbr\u003eExtended-release (XR) formulation\u003cbr\u003eDose as directed by the physician, usually taken with food to reduce GI side effects\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Side Effects:\u003cbr\u003eComponent    Common Adverse Effects\u003cbr\u003eEmpagliflozin    Urinary tract infection, female genital fungal infections\u003cbr\u003eMetformin    Diarrhea, nausea, vomiting, flatulence, abdominal pain, indigestion, weakness, headache\u003cbr\u003e________________________________________\u003cbr\u003e🔄 Drug Interactions:\u003cbr\u003eDiuretics → Risk of volume depletion\u003cbr\u003ePositive urine glucose test → Possible false positives\u003cbr\u003e1,5-AG assay → Not reliable for glycemic control monitoring\u003cbr\u003eMetformin Interactions:\u003cbr\u003eDrugs affecting renal function (e.g. ranolazine, cimetidine, dolutegravir)\u003cbr\u003eOthers: corticosteroids, oral contraceptives, thyroid hormones, phenytoin, NSAIDs, nifedipine\u003cbr\u003e________________________________________\u003cbr\u003e📌 Indications:\u003cbr\u003eAdjunct to diet and exercise for adults with type 2 diabetes:\u003cbr\u003eNot adequately controlled on metformin or empagliflozin alone\u003cbr\u003eAlready on both medications as separate tablets\u003cbr\u003e________________________________________\u003cbr\u003e🚫 When Not to Use (Contraindications):\u003cbr\u003eRenal impairment, end-stage renal disease (ESRD), or on dialysis\u003cbr\u003eMetabolic acidosis (e.g., diabetic ketoacidosis)\u003cbr\u003eKnown hypersensitivity to empagliflozin or metformin\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Precautions:\u003cbr\u003eKeep out of reach of children\u003cbr\u003eStore in a cool, dry place, away from light and heat\u003cbr\u003eUse caution in elderly patients or those on diuretics\u003cbr\u003e________________________________________\u003cbr\u003e⚠️ Warnings:\u003cbr\u003eLactic Acidosis (Metformin):\u003cbr\u003eRare but serious – early signs include malaise, muscle pain, abdominal pain, slow heart rate, hypothermia, or breathing difficulties. May be fatal if untreated.\u003cbr\u003eHypotension (Empagliflozin):\u003cbr\u003eRisk due to volume depletion. Monitor renal function and blood pressure, especially in elderly, those on diuretics, or with low systolic pressure.\u003cbr\u003eKetoacidosis (Empagliflozin):\u003cbr\u003eRare but serious – may occur even with normal blood sugar levels. Do not use in patients with type 1 diabetes. Discontinue if ketoacidosis is suspected.\u003cbr\u003e________________________________________\u003cbr\u003e🤰 Pregnancy Category:\u003cbr\u003eConsult a physician before use. Safety not established in pregnancy or during breastfeeding.\u003cbr\u003e________________________________________\u003cbr\u003e📦 Storage:\u003cbr\u003e✅ Yes\u003cbr\u003eStore at room temperature, protected from light and heat\u003cbr\u003e\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53336112759115,"sku":null,"price":440.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/download_1.jpg?v=1757313510","url":"https:\/\/wellnesspharmacy.pk\/products\/empagen-m-xr-tablets-12-5-1000mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}