{"product_id":"eskem-capsules-20mg","title":"Eskem Capsules 20MG","description":"\u003cp\u003eMedicine Name: Eskem Capsules 20mg\u003cbr\u003eEskem Capsules Specification\u003cbr\u003eRequires Prescription\u003cbr\u003eYes\u003cbr\u003eGenerics\u003cbr\u003eEsomeprazole\u003cbr\u003eUsed For\u003cbr\u003e Acidity\u003cbr\u003e Ulcers\u003cbr\u003e Heartburn\u003cbr\u003e GERD (Gastroesophageal Reflux Disease)\u003cbr\u003e Gastritis\u003cbr\u003eHow It Works\u003cbr\u003eEsomeprazole is a proton pump inhibitor (PPI) that irreversibly binds to the H⁺\/K⁺ ATPase\u003cbr\u003eenzyme in the gastric parietal cells. This enzyme is the final step in the production of\u003cbr\u003ehydrochloric acid in the stomach. Inhibition leads to a significant reduction in acid secretion,\u003cbr\u003ethereby increasing gastric pH and alleviating symptoms related to excess stomach acid.\u003cbr\u003eEskem Capsules Usage and Safety\u003cbr\u003eDosage\u003cbr\u003eEsomeprazole (as directed by your physician)\u003cbr\u003eSide Effects\u003cbr\u003e Common:\u003cbr\u003eHeadache, gastrointestinal upset, skin reactions, dry mouth\u003cbr\u003e Rare:\u003cbr\u003eAngioedema, anaphylaxis, fundic gland polyps\u003cbr\u003eDrug Interactions\u003cbr\u003e Medications to watch for interactions:\u003cbr\u003eo Antiepileptics: Phenytoin\u003cbr\u003eo Anticoagulants: Warfarin\u003cbr\u003eo Antiplatelet: Clopidogrel (avoid co-administration)\u003cbr\u003eo Antifungals: Ketoconazole, Itraconazole, Voriconazole\u003cbr\u003eo Sedatives\/Anxiolytics: Diazepam\u003cbr\u003eo Antidepressants: Citalopram, Imipramine, Clomipramine\u003cbr\u003eo Immunosuppressants: Tacrolimus\u003cbr\u003eo Others: Digoxin, Erlotinib, Methotrexate\u003cbr\u003eo CYP3A4 inhibitors or inducers\u003cbr\u003eIndication\u003cbr\u003eFor the treatment and management of:\u003cbr\u003e Heartburn\u003cbr\u003e GERD\u003cbr\u003e Gastritis\u003cbr\u003e Gastric or duodenal ulcers\u003cbr\u003eWhen Not to Use (Contraindications)\u003cbr\u003e Known hypersensitivity to Esomeprazole or any other proton pump inhibitor (PPI)\u003cbr\u003e History of hypersensitivity reactions such as:\u003cbr\u003eo Angioedema\u003cbr\u003eo Anaphylaxis\u003cbr\u003eo Bronchospasm\u003cbr\u003eo Acute interstitial nephritis\u003cbr\u003eo Urticaria\u003cbr\u003eEskem Capsules Precautions\u003cbr\u003ePrecaution\u003cbr\u003eLong-term daily use (more than 3 years) may impair absorption of vitamin B12\u003cbr\u003e(cyanocobalamin), possibly leading to deficiency.\u003cbr\u003eEskem Capsules Warnings\u003cbr\u003eWarning 1:\u003cbr\u003eProlonged PPI use may lead to hypomagnesemia. Monitor magnesium levels during long-term\u003cbr\u003etherapy.\u003cbr\u003eWarning 2:\u003cbr\u003eChronic or high-dose use of PPIs may increase the risk of osteoporosis-related fractures (hip,\u003cbr\u003ewrist, spine).\u003cbr\u003eWarning 3:\u003cbr\u003eAvoid co-administration of Esomeprazole with clopidogrel, as it may reduce the effectiveness\u003cbr\u003eof clopidogrel.\u003cbr\u003ePregnancy Category\u003cbr\u003eAlways consult your physician before using during pregnancy.\u003cbr\u003eStorage\u003cbr\u003eYes — Store at room temperature, protected from direct light and heat\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53280050282827,"sku":null,"price":190.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7182.jpg?v=1756539519","url":"https:\/\/wellnesspharmacy.pk\/products\/eskem-capsules-20mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}