{"product_id":"gouric-tablets-40mg","title":"Gouric Tablets 40mg","description":"\u003cp\u003e. Medicine Name: Gouric Tablets 40mg\u003cbr\u003eGouric Tablets Specification\u003cbr\u003eRequires Prescription:\u003cbr\u003e✅ Yes\u003cbr\u003eGeneric Name:\u003cbr\u003eFebuxostat\u003cbr\u003eUsed For:\u003cbr\u003e Chronic management of hyperuricemia in patients with gout\u003cbr\u003eHow it Works:\u003cbr\u003eFebuxostat is a non-purine selective xanthine oxidase (XO) inhibitor. It lowers serum uric\u003cbr\u003eacid levels by inhibiting XO, the enzyme responsible for converting:\u003cbr\u003e Hypoxanthine → Xanthine → Uric Acid\u003cbr\u003eThis reduction in uric acid helps prevent gout attacks.\u003cbr\u003eDosage:\u003cbr\u003e Febuxostat (dose individualized by physician)\u003cbr\u003eSide Effects:\u003cbr\u003eCommon:\u003cbr\u003e Headache, diarrhea, nausea, rash, liver function test (LFT) abnormalities\u003cbr\u003eUncommon:\u003cbr\u003e Increase in blood amylase, creatinine, urea, LDH, triglycerides\u003cbr\u003e Decreased platelet count, hemoglobin\u003cbr\u003e Dizziness, somnolence, paraesthesia, altered taste\u003cbr\u003e GI symptoms (abdominal pain, reflux, vomiting, constipation, flatulence, dyspepsia)\u003cbr\u003e Nephrolithiasis, hematuria, frequent urination\u003cbr\u003e Skin reactions (dermatitis, urticaria, pruritus)\u003cbr\u003e Joint and muscle pain (arthralgia, arthritis, myalgia, cramps)\u003cbr\u003e Weight gain, increased appetite\u003cbr\u003e Hypertension, flushing, edema\u003cbr\u003e Flu-like symptoms, reduced libido\u003cbr\u003eRare:\u003cbr\u003e Palpitations, renal insufficiency, weakness (asthenia), thirst, nervousness, insomnia\u003cbr\u003eDrug Interactions:\u003cbr\u003e Naproxen, NSAIDs, Probenecid\u003cbr\u003e Inhibitors of glucuronidation\u003cbr\u003e UGT enzyme substrates\u003cbr\u003e Contraindicated with azathioprine, mercaptopurine, theophylline\u003cbr\u003eContraindications (When Not to Use):\u003cbr\u003e Hypersensitivity to febuxostat or any excipient\u003cbr\u003e Patients using:\u003cbr\u003e▪ Azathioprine\u003cbr\u003e▪ Mercaptopurine\u003cbr\u003e▪ Theophylline\u003cbr\u003e Asymptomatic hyperuricemia\u003cbr\u003ePrecautions:\u003cbr\u003e Not recommended in patients with ischemic heart disease or congestive heart failure\u003cbr\u003eWarnings:\u003cbr\u003e1. Gout Flares:\u003cbr\u003e Increased flares may occur after starting febuxostat due to urate mobilization\u003cbr\u003e Prophylactic NSAID or colchicine is recommended at initiation\u003cbr\u003e2. High Urate Formation Conditions:\u003cbr\u003e Not recommended in conditions like malignancy or Lesch-Nyhan syndrome (risk of\u003cbr\u003exanthine urinary deposition)\u003cbr\u003e3. Liver Monitoring:\u003cbr\u003e Liver function tests advised at 2 and 4 months, and periodically afterward\u003cbr\u003ePregnancy Category:\u003cbr\u003e Always consult a physician before use\u003cbr\u003eStorage:\u003cbr\u003e✅ Yes\u003cbr\u003e Store at room temperature, away from light and heat\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53346627649867,"sku":null,"price":595.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_6895.jpg?v=1757400700","url":"https:\/\/wellnesspharmacy.pk\/products\/gouric-tablets-40mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}