{"product_id":"motilium-120ml-suspension-5mg-5ml","title":"Motilium 120Ml Suspension 5mg\/5ml","description":"\u003cp\u003eRequires Prescription:\u003cbr\u003eYes\u003cbr\u003eGenerics (Active Ingredient):\u003cbr\u003e Domperidone Maleate\u003cbr\u003eUsed For:\u003cbr\u003e Nausea\u003cbr\u003e Vomiting\u003cbr\u003eHow It Works:\u003cbr\u003eDomperidone’s antiemetic effect is due to a combination of:\u003cbr\u003e Peripheral gastrokinetic action (enhances gastrointestinal motility)\u003cbr\u003e Dopamine receptor antagonism in the chemoreceptor trigger zone (area postrema outside\u003cbr\u003ethe blood-brain barrier), reducing nausea and vomiting.\u003cbr\u003eUsage and Safety\u003cbr\u003eDosage:\u003cbr\u003eAs prescribed by the healthcare provider.\u003cbr\u003eSide Effects:\u003cbr\u003e Depression (2.5%)\u003cbr\u003e Anxiety (1.6%)\u003cbr\u003e Decreased or loss of libido\u003cbr\u003e Headache (5.6%)\u003cbr\u003e Somnolence (2.5%)\u003cbr\u003e Akathisia (restlessness) (1%)\u003cbr\u003e Diarrhea (5.2%)\u003cbr\u003e Rash (2.8%)\u003cbr\u003e Pruritus (itching) (1.7%)\u003cbr\u003e Breast enlargement \/ Gynaecomastia (5.3%)\u003cbr\u003e Breast tenderness (4.4%)\u003cbr\u003e Galactorrhea (3.3%)\u003cbr\u003e Amenorrhea (2.9%)\u003cbr\u003e Breast pain (2.3%)\u003cbr\u003e Menstruation irregularities (2.0%)\u003cbr\u003e Lactation disorder (1.6%)\u003cbr\u003eDrug Interactions:\u003cbr\u003ePotential interactions with:\u003cbr\u003e CYP3A4 inhibitors (e.g., indinavir)\u003cbr\u003e Class IA antiarrhythmics (e.g., disopyramide, quinidine)\u003cbr\u003e Class III antiarrhythmics (e.g., amiodarone, sotalol)\u003cbr\u003e Certain antipsychotics (e.g., haloperidol, pimozide)\u003cbr\u003e Certain antidepressants (e.g., citalopram, escitalopram)\u003cbr\u003e Certain antibiotics (e.g., levofloxacin, moxifloxacin)\u003cbr\u003e Certain antifungals (e.g., pentamidine)\u003cbr\u003e Certain antimalarials (e.g., halofantrine)\u003cbr\u003e Certain GI drugs (e.g., dolasetron)\u003cbr\u003e Certain cancer drugs (e.g., toremifene, vandetanib)\u003cbr\u003e Others (e.g., methadone, bepridil)\u003cbr\u003eIndication:\u003cbr\u003eTreatment of nausea and vomiting.\u003cbr\u003eWhen Not to Use:\u003cbr\u003e Moderate to severe hepatic impairment\u003cbr\u003e Known prolonged cardiac conduction intervals (especially QTc prolongation)\u003cbr\u003e Significant electrolyte disturbances\u003cbr\u003e Underlying cardiac diseases such as congestive heart failure\u003cbr\u003ePrecautions:\u003cbr\u003e Increased risk of serious ventricular arrhythmias and sudden cardiac death has been noted\u003cbr\u003eepidemiologically.\u003cbr\u003e Use with caution especially in patients over 60 years of age.\u003cbr\u003e Monitor for cardiac symptoms during treatment.\u003cbr\u003eWarnings:\u003cbr\u003e1. Patients over 60 should consult their physician before use.\u003cbr\u003e2. Avoid use if prolonged QTc or significant electrolyte disturbances exist.\u003cbr\u003e3. Stop treatment immediately if cardiac arrhythmia symptoms appear and seek medical\u003cbr\u003eadvice.\u003cbr\u003ePregnancy Category:\u003cbr\u003eAlways consult your physician before use during pregnancy or breastfeeding.\u003cbr\u003eStorage:\u003cbr\u003eYes – Store at room temperature, away from direct light and heat.\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53265787257163,"sku":null,"price":180.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7363.jpg?v=1756365970","url":"https:\/\/wellnesspharmacy.pk\/products\/motilium-120ml-suspension-5mg-5ml","provider":"The Wellness Hospital","version":"1.0","type":"link"}