{"product_id":"nexum-capsules-20mg","title":"Nexum Capsules 20mg","description":"\u003cp\u003eMedicine Name: Nexum Capsules 20mg\u003cbr\u003e✅ Nexum Capsules Specification\u003cbr\u003e📌 Requires Prescription\u003cbr\u003eYes\u003cbr\u003e💊 Generic Name\u003cbr\u003eEsomeprazole\u003cbr\u003e⚕️ Used For\u003cbr\u003e Acidity\u003cbr\u003e Heartburn\u003cbr\u003e Gastroesophageal Reflux Disease (GERD)\u003cbr\u003e Gastritis\u003cbr\u003e Peptic Ulcers\u003cbr\u003e⚙️ How It Works\u003cbr\u003eEsomeprazole is a proton pump inhibitor (PPI) that irreversibly binds to H⁺\/K⁺ ATPase\u003cbr\u003eenzymes in gastric parietal cells.\u003cbr\u003e This inhibits the final step in gastric acid secretion, leading to a marked reduction in\u003cbr\u003ehydrochloric acid and increased gastric pH.\u003cbr\u003e Provides relief from acid-related disorders and promotes healing of the gastric lining.\u003cbr\u003e⚕️ Dosage\u003cbr\u003e As directed by a physician\u003cbr\u003e Usual adult dosage: 20–40 mg once daily, depending on condition\u003cbr\u003e⚠️ Side Effects\u003cbr\u003e🔹 Common:\u003cbr\u003e Headache\u003cbr\u003e Gastrointestinal upset (nausea, abdominal pain, constipation, diarrhea)\u003cbr\u003e Dry mouth\u003cbr\u003e Skin reactions (rash, pruritus)\u003cbr\u003e🔹 Rare:\u003cbr\u003e Angioedema\u003cbr\u003e Anaphylaxis\u003cbr\u003e Fundic gland polyps\u003cbr\u003e🔄 Drug Interactions\u003cbr\u003eMay interact with:\u003cbr\u003e Antiepileptics: Phenytoin\u003cbr\u003e Anticoagulants: Warfarin\u003cbr\u003e Antiplatelets: Clopidogrel (avoid concomitant use)\u003cbr\u003e Antifungals: Ketoconazole, itraconazole, voriconazole\u003cbr\u003e CNS agents: Diazepam, citalopram, imipramine, clomipramine\u003cbr\u003e Immunosuppressants: Tacrolimus\u003cbr\u003e Others: Digoxin, erlotinib, methotrexate\u003cbr\u003e CYP3A4 inhibitors\/inducers: e.g. Rifampicin, St. John's Wort\u003cbr\u003e🚫 When Not to Use\u003cbr\u003eContraindicated in patients with:\u003cbr\u003e Hypersensitivity to esomeprazole or other PPIs\u003cbr\u003e History of severe allergic reactions (e.g., angioedema, anaphylaxis, bronchospasm,\u003cbr\u003eurticaria, acute interstitial nephritis)\u003cbr\u003e⚖️ Precautions\u003cbr\u003e Long-term use (\u0026gt;3 years) may cause vitamin B12 (cyanocobalamin) deficiency due to\u003cbr\u003ereduced gastric acid needed for its absorption.\u003cbr\u003e⚠️ Warnings\u003cbr\u003e⚠️ 1. Hypomagnesemia\u003cbr\u003e Rare with long-term use\u003cbr\u003e Monitor magnesium levels, especially with diuretics or digoxin\u003cbr\u003e⚠️ 2. Fracture Risk\u003cbr\u003e Long-term or high-dose PPI therapy may increase risk of osteoporosis-related fractures\u003cbr\u003e(hip, wrist, spine), especially in elderly\u003cbr\u003e⚠️ 3. Interaction with Clopidogrel\u003cbr\u003e Avoid concomitant use; may reduce clopidogrel’s antiplatelet efficacy\u003cbr\u003e🤰 Pregnancy Category\u003cbr\u003e Consult a physician before use during pregnancy or lactation\u003cbr\u003e⚕️ Storage\u003cbr\u003eYes\u003cbr\u003e Store at room temperature\u003cbr\u003e Protect from direct light and heat\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53280733397323,"sku":null,"price":375.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7219.jpg?v=1756547538","url":"https:\/\/wellnesspharmacy.pk\/products\/nexum-capsules-20mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}