{"product_id":"novoteph-capsules-40mg","title":"Novoteph Capsules 40MG","description":"\u003cp\u003e Medicine Name: Novoteph Capsules 40mg\u003cbr\u003e✅ Novoteph Capsules Specification\u003cbr\u003e📌 Requires Prescription\u003cbr\u003eYes\u003cbr\u003e💊 Generic Name\u003cbr\u003eEsomeprazole\u003cbr\u003e⚕️ Used For\u003cbr\u003e Acidity\u003cbr\u003e Heartburn\u003cbr\u003e Gastroesophageal Reflux Disease (GERD)\u003cbr\u003e Gastritis\u003cbr\u003e Peptic Ulcers\u003cbr\u003e⚙️ How It Works\u003cbr\u003eEsomeprazole is a proton pump inhibitor (PPI) that acts by irreversibly binding to the H⁺\/K⁺\u003cbr\u003eATPase enzyme on the gastric parietal cells.\u003cbr\u003e This enzyme is the final step in acid secretion in the stomach.\u003cbr\u003e Inhibiting it leads to a significant reduction in hydrochloric acid production, thereby\u003cbr\u003eraising gastric pH and relieving acid-related symptoms.\u003cbr\u003e⚕️ Dosage\u003cbr\u003e As directed by a physician\u003cbr\u003e Usual adult dose: 20–40 mg once daily, depending on the condition and severity\u003c\/p\u003e\n\u003cp\u003e⚠️ Side Effects\u003cbr\u003e🔹 Common:\u003cbr\u003e Headache\u003cbr\u003e Gastrointestinal upset (e.g., nausea, diarrhea, abdominal pain)\u003cbr\u003e Skin reactions (rash, itching)\u003cbr\u003e Dry mouth\u003cbr\u003e🔹 Rare:\u003cbr\u003e Angioedema\u003cbr\u003e Anaphylaxis\u003cbr\u003e Fundic gland polyps (especially with long-term use)\u003cbr\u003e🔄 Drug Interactions\u003cbr\u003eMay interact with:\u003cbr\u003e Antiepileptics: Phenytoin\u003cbr\u003e Anticoagulants: Warfarin\u003cbr\u003e Antiplatelets: Clopidogrel (avoid combination)\u003cbr\u003e Antifungals: Ketoconazole, itraconazole, voriconazole\u003cbr\u003e CNS drugs: Diazepam, citalopram, imipramine, clomipramine\u003cbr\u003e Immunosuppressants: Tacrolimus\u003cbr\u003e Others:\u003cbr\u003eo Digoxin\u003cbr\u003eo Erlotinib\u003cbr\u003eo Methotrexate\u003cbr\u003eo CYP3A4 inhibitors\/inducers (e.g., St. John's Wort, rifampicin)\u003cbr\u003e🚫 When Not to Use\u003cbr\u003eContraindicated in:\u003cbr\u003e Patients with known hypersensitivity to PPIs\u003cbr\u003e History of severe allergic reactions, including:\u003cbr\u003eo Angioedema\u003cbr\u003eo Anaphylaxis\u003cbr\u003eo Urticaria\u003cbr\u003eo Bronchospasm\u003cbr\u003eo Acute interstitial nephritis\u003cbr\u003e⚖️ Precautions\u003cbr\u003e Long-term daily use (e.g., \u0026gt;3 years) may lead to vitamin B12 (cyanocobalamin)\u003cbr\u003edeficiency due to reduced gastric acid needed for absorption.\u003cbr\u003e⚠️ Warnings\u003cbr\u003e⚠️ 1. Hypomagnesemia\u003cbr\u003e Rare but serious; monitor serum magnesium in long-term users or those on digoxin or\u003cbr\u003ediuretics.\u003cbr\u003e⚠️ 2. Fracture Risk\u003cbr\u003e Long-term or high-dose PPI use may increase the risk of osteoporosis-related fractures\u003cbr\u003e(hip, wrist, spine), especially in the elderly.\u003cbr\u003e⚠️ 3. Clopidogrel Interaction\u003cbr\u003e Avoid concurrent use due to reduced efficacy of clopidogrel's antiplatelet effect.\u003cbr\u003e🤰 Pregnancy Category\u003cbr\u003e Consult your physician before use during pregnancy or lactation.\u003cbr\u003e⚕️ Storage\u003cbr\u003eYes\u003cbr\u003e Store at room temperature\u003cbr\u003e Protect from direct light and heat\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53280681427275,"sku":null,"price":490.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7220.jpg?v=1756547184","url":"https:\/\/wellnesspharmacy.pk\/products\/novoteph-capsules-40mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}