{"product_id":"ruling-capsules-40mg","title":"Ruling Capsules 40mg","description":"\u003cp\u003eRuling Capsules Specification\u003cbr\u003eRequires Prescription (YES\/NO)\u003cbr\u003eYes\u003cbr\u003eGenerics\u003cbr\u003eOmeprazole\u003cbr\u003eUsed For\u003cbr\u003eGastroesophageal Reflux Disease (GERD)\u003cbr\u003eHow It Works\u003cbr\u003eOmeprazole inhibits gastric acid secretion by irreversibly blocking the hydrogen\/potassium\u003cbr\u003eATPase enzyme system (proton pump) in the gastric parietal cells. This effect reduces both basal\u003cbr\u003eand stimulated acid secretion, regardless of the stimulus.\u003cbr\u003eUsage and Safety\u003cbr\u003eDosage\u003cbr\u003eOmeprazole (as prescribed by the physician)\u003cbr\u003eSide Effects\u003cbr\u003e Common:\u003cbr\u003eo Headache\u003cbr\u003eo Diarrhea, constipation, abdominal pain, nausea\/vomiting, flatulence\u003cbr\u003e Uncommon:\u003cbr\u003eo Dizziness, paraesthesia, somnolence, insomnia, vertigo\u003cbr\u003eo Increased liver enzymes\u003cbr\u003eo Rash, pruritis, urticaria\u003cbr\u003eo Malaise\u003cbr\u003e Rare:\u003cbr\u003eo Reversible mental confusion, agitation, aggression, depression, hallucinations\u003cbr\u003e(mostly in severely ill patients)\u003cbr\u003eo Gynecomastia\u003cbr\u003eDrug Interactions\u003cbr\u003eMay interact with:\u003cbr\u003e Ketoconazole, itraconazole\u003cbr\u003e Diazepam, citalopram, imipramine, clomipramine, phenytoin\u003cbr\u003e Atazanavir, Digoxin, Clopidogrel\u003cbr\u003e Posaconazole, erlotinib, Saquinavir, Tacrolimus\u003cbr\u003e Methotrexate, clarithromycin\u003cbr\u003e CYP2C19 and CYP3A4 substrates (e.g., rifampicin, St John's wort)\u003cbr\u003eIndications\u003cbr\u003e Treatment of erosive reflux esophagitis\u003cbr\u003e Long-term management of healed esophagitis to prevent relapse\u003cbr\u003e Symptomatic treatment of GERD\u003cbr\u003eWhen Not to Use (Contraindications)\u003cbr\u003e Known hypersensitivity to omeprazole or substituted benzimidazoles\u003cbr\u003e Concurrent use with nelfinavir\u003cbr\u003ePrecautions\u003cbr\u003e Omeprazole may reduce vitamin B12 absorption due to reduced stomach acid\u003cbr\u003e(hypochlorhydria or achlorhydria). This is important for patients with low B12 stores or\u003cbr\u003ethose on long-term therapy.\u003cbr\u003eWarnings\u003cbr\u003e1. When gastric ulcer is suspected, malignancy should be ruled out as symptom relief may\u003cbr\u003edelay diagnosis.\u003cbr\u003e2. Long-term or high-dose use (over one year) may increase the risk of fractures (hip, wrist,\u003cbr\u003espine), especially in elderly or at-risk patients.\u003cbr\u003e3. Dose adjustment may be necessary in patients with impaired liver function due to\u003cbr\u003eincreased drug bioavailability and half-life.\u003cbr\u003eAdditional Information\u003cbr\u003ePregnancy Category: Always consult your physician before using this medicine.\u003cbr\u003eStorage (YES\/NO)\u003cbr\u003eYes – Store at room temperature, away from direct light and heat.\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53294854472011,"sku":null,"price":240.0,"currency_code":"PKR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7232.jpg?v=1756786302","url":"https:\/\/wellnesspharmacy.pk\/products\/ruling-capsules-40mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}