{"product_id":"septran-50ml-paediatric-suspension-40mg-200mg","title":"Septran 50Ml Paediatric Suspension 40mg\/200mg","description":"\u003cp\u003eRequires Prescription:\u003cbr\u003eYes\u003cbr\u003eGenerics:\u003cbr\u003e Sulfamethoxazole\u003cbr\u003e Trimethoprim\u003cbr\u003eUsed For:\u003cbr\u003eBacterial Infections, including:\u003cbr\u003e Respiratory tract infections\u003cbr\u003e Urinary tract infections\u003cbr\u003e Gastrointestinal infections\u003cbr\u003e Ear infections\u003cbr\u003e Certain forms of pneumonia\u003cbr\u003e Preventive use in immunocompromised patients (as advised by a doctor)\u003cbr\u003eHow It Works:\u003cbr\u003eSeptran is a combination of Sulfamethoxazole and Trimethoprim that works synergistically to\u003cbr\u003einhibit folate synthesis in bacteria:\u003cbr\u003e Sulfamethoxazole blocks the conversion of para-aminobenzoic acid to dihydrofolic acid.\u003cbr\u003e Trimethoprim inhibits the enzyme dihydrofolate reductase, blocking the next step in\u003cbr\u003efolate metabolism.\u003cbr\u003eThis dual-action kills or inhibits the growth of susceptible bacteria.\u003cbr\u003eUsage and Safety\u003cbr\u003eDosage:\u003cbr\u003eAs prescribed by the physician depending on age, weight, and severity of infection. (Each 5ml\u003cbr\u003econtains Sulfamethoxazole 200mg + Trimethoprim 40mg)\u003cbr\u003eSide Effects:\u003cbr\u003e Gastrointestinal: Nausea, vomiting, diarrhea, abdominal pain, glossitis, dry mouth\u003cbr\u003e Hematologic: Leukopenia, thrombocytopenia, megaloblastic anemia, hemolytic anemia\u003cbr\u003e(especially in G6PD-deficient patients)\u003cbr\u003e Musculoskeletal: Myalgia, arthralgia, rhabdomyolysis\u003cbr\u003e Dermatologic: Alopecia, rash\u003cbr\u003e Other: Fatigue, insomnia, epistaxis, edema, vision problems\u003cbr\u003eDrug Interactions:\u003cbr\u003e Major Interactions: Warfarin, Methotrexate, Phenytoin, Zidovudine, Cyclosporin\u003cbr\u003e Others: Rifampicin, Thiazides, Pyrimethamine, Digoxin, Lamivudine, Azathioprine,\u003cbr\u003eRepaglinide, Folinic acid\u003cbr\u003eIndication:\u003cbr\u003eUsed to treat or prevent infections caused by susceptible bacteria. It is important that the use\u003cbr\u003eis based on clinical evidence or strong suspicion of bacterial infection.\u003cbr\u003eWhen Not to Use:\u003cbr\u003e Known allergy to Trimethoprim or Sulfonamides\u003cbr\u003e Megaloblastic anemia due to folate deficiency\u003cbr\u003e Pregnant women at term\u003cbr\u003e Nursing mothers\u003cbr\u003e Infants under 2 months of age\u003cbr\u003ePrecautions:\u003cbr\u003e Avoid use without confirmed or suspected bacterial infection to prevent antibiotic\u003cbr\u003eresistance\u003cbr\u003e Monitor renal and liver function during therapy\u003cbr\u003e Monitor folate levels in high-risk groups (elderly, alcoholics, malnourished, those on\u003cbr\u003elong-term anticonvulsants)\u003cbr\u003eWarnings:\u003cbr\u003eWarning 1\u003cbr\u003eUse with caution in patients with renal or hepatic impairment, folate deficiency, or asthma.\u003cbr\u003eWarning 2\u003cbr\u003eEnsure adequate fluid intake to prevent crystalluria and kidney stone formation.\u003cbr\u003eWarning 3\u003cbr\u003eAntibiotic-associated diarrhea can occur during or after treatment. Contact a physician if\u003cbr\u003epersistent or severe diarrhea occurs, especially if it contains blood.\u003cbr\u003ePregnancy Category:\u003cbr\u003eAlways consult your physician before use during pregnancy or breastfeeding.\u003cbr\u003eStorage:\u003cbr\u003eYes – Store at room temperature, away from direct light and heat.\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53266495144267,"sku":null,"price":66.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7351_606a616c-5709-4da7-b4d6-4940c5d053ac.jpg?v=1756372759","url":"https:\/\/wellnesspharmacy.pk\/products\/septran-50ml-paediatric-suspension-40mg-200mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}