{"product_id":"septran-ds-50ml-suspension-80mg-400mg","title":"Septran Ds 50Ml Suspension 80mg\/400mg","description":"\u003cp\u003eRequires Prescription:\u003cbr\u003eYes\u003cbr\u003eGenerics:\u003cbr\u003e Trimethoprim 80mg\u003cbr\u003e Sulfamethoxazole 400mg\u003cbr\u003e(Per 5ml)\u003cbr\u003eUsed For:\u003cbr\u003eTreatment and prevention of bacterial infections, including:\u003cbr\u003e Respiratory tract infections\u003cbr\u003e Urinary tract infections\u003cbr\u003e Ear infections\u003cbr\u003e Gastrointestinal infections\u003cbr\u003e Certain types of pneumonia\u003cbr\u003e Prophylaxis in immunocompromised individuals (on physician's advice)\u003cbr\u003eHow It Works:\u003cbr\u003eSeptran DS is a broad-spectrum antibiotic combination:\u003cbr\u003e Sulfamethoxazole inhibits bacterial synthesis of dihydrofolate by blocking paraaminobenzoic acid (PABA) utilization.\u003cbr\u003e Trimethoprim inhibits dihydrofolate reductase, preventing the conversion of\u003cbr\u003edihydrofolate to tetrahydrofolate, a key step in DNA synthesis.\u003cbr\u003eTogether, they provide a synergistic bactericidal effect.\u003cbr\u003eUsage and Safety\u003cbr\u003eDosage:\u003cbr\u003eAs prescribed by a physician, based on age, weight, and infection severity.\u003cbr\u003eSide Effects:\u003cbr\u003e Gastrointestinal: Nausea, vomiting, diarrhea, gastritis, stomatitis, glossitis, abdominal\u003cbr\u003epain\u003cbr\u003e Hematologic: Leukopenia, thrombocytopenia, megaloblastic anemia, hemolytic anemia,\u003cbr\u003epurpura\u003cbr\u003e Musculoskeletal: Arthralgia, myalgia, rhabdomyolysis\u003cbr\u003e Neurological: Insomnia, fatigue, weakness, dizziness\u003cbr\u003e Others: Alopecia, vision disturbances, edema, photosensitivity, rash\u003cbr\u003eDrug Interactions:\u003cbr\u003eMay interact with:\u003cbr\u003e Anticoagulants: Warfarin\u003cbr\u003e Immunosuppressants: Cyclosporin\u003cbr\u003e Antivirals: Zidovudine, Lamivudine\u003cbr\u003e Antiepileptics: Phenytoin\u003cbr\u003e Others: Methotrexate, Rifampicin, Pyrimethamine, Thiazides, Digoxin, Azathioprine,\u003cbr\u003eFolinic acid, Repaglinide\u003cbr\u003eIndication:\u003cbr\u003eUsed to treat or prevent infections that are proven or strongly suspected to be caused by\u003cbr\u003esusceptible bacteria.\u003cbr\u003eWhen Not to Use:\u003cbr\u003e Known hypersensitivity to Trimethoprim or Sulfonamides\u003cbr\u003e Megaloblastic anemia due to folate deficiency\u003cbr\u003e Pregnant patients at term\u003cbr\u003e Nursing mothers\u003cbr\u003e Infants \u0026lt; 2 months of age\u003cbr\u003ePrecautions:\u003cbr\u003e Avoid unnecessary use to reduce risk of antibiotic resistance\u003cbr\u003e Use with caution in renal or hepatic impairment\u003cbr\u003e Monitor folate levels in high-risk patients (e.g. elderly, malnourished, chronic alcohol\u003cbr\u003eusers)\u003cbr\u003eWarnings:\u003cbr\u003eWarning 1:\u003cbr\u003eUse cautiously in patients with renal\/liver disease, folate deficiency, or severe\u003cbr\u003eallergies\/asthma.\u003cbr\u003eWarning 2:\u003cbr\u003eEnsure adequate hydration to prevent crystalluria and kidney stones.\u003cbr\u003eWarning 3:\u003cbr\u003ePost-antibiotic diarrhea (including C. difficile-associated diarrhea) may occur. Seek medical\u003cbr\u003eattention if severe diarrhea develops during or after treatment.\u003cbr\u003ePregnancy Category:\u003cbr\u003eConsult your physician before using during pregnancy or breastfeeding.\u003cbr\u003eStorage:\u003cbr\u003eYes – Store at room temperature, away from direct light and heat.\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53266536497483,"sku":null,"price":91.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7351_4d1cf68e-92c8-4089-90a2-2509bbf4cb93.jpg?v=1756372900","url":"https:\/\/wellnesspharmacy.pk\/products\/septran-ds-50ml-suspension-80mg-400mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}