{"product_id":"teph-capsules-40mg","title":"Teph Capsules 40MG","description":"\u003cp\u003eMedicine Name: Teph Insta Capsules 40mg\u003cbr\u003eTeph Insta Specification\u003cbr\u003eRequires Prescription\u003cbr\u003eYes\u003cbr\u003eGeneric Composition\u003cbr\u003e Omeprazole\u003cbr\u003e Sodium Bicarbonate\u003cbr\u003eTherapeutic Use\u003cbr\u003eIndicated for the Treatment of:\u003cbr\u003e Gastroesophageal Reflux Disease (GERD):\u003cbr\u003eo Treatment of erosive reflux esophagitis\u003cbr\u003eo Long-term management of healed esophagitis to prevent relapse\u003cbr\u003eo Symptomatic treatment of GERD\u003cbr\u003eMechanism of Action\u003cbr\u003e Omeprazole is a proton pump inhibitor (PPI) that reduces gastric acid secretion by\u003cbr\u003eirreversibly blocking the H⁺\/K⁺ ATPase enzyme system (the proton pump) in gastric\u003cbr\u003eparietal cells.\u003cbr\u003e Sodium Bicarbonate:\u003cbr\u003eo Acts as an antacid, quickly neutralizing stomach acid.\u003cbr\u003eo Protects omeprazole from gastric degradation, allowing for faster and more\u003cbr\u003eeffective absorption.\u003cbr\u003e The combined effect is a rapid onset of acid suppression and prolonged relief from\u003cbr\u003eacid-related symptoms.\u003cbr\u003eDosage\u003cbr\u003e As prescribed by a physician\u003cbr\u003e Typical formulations: Capsules or powder for oral suspension containing Omeprazole\u003cbr\u003e+ Sodium Bicarbonate\u003cbr\u003eSide Effects\u003cbr\u003eCommon:\u003cbr\u003e CNS: Headache\u003cbr\u003e GI: Diarrhea, constipation, abdominal pain, nausea, vomiting, flatulence\u003cbr\u003eUncommon:\u003cbr\u003e CNS: Dizziness, paraesthesia, drowsiness, insomnia, vertigo\u003cbr\u003e Hepatic: Elevated liver enzymes\u003cbr\u003e Skin: Rash, pruritus, urticaria\u003cbr\u003e General: Malaise\u003cbr\u003eRare:\u003cbr\u003e CNS (especially in severely ill patients): Mental confusion, agitation, aggression,\u003cbr\u003edepression, hallucinations\u003cbr\u003e Endocrine: Gynecomastia\u003cbr\u003eDrug Interactions\u003cbr\u003eMay interact with:\u003cbr\u003e Antifungals: Ketoconazole, itraconazole, posaconazole\u003cbr\u003e CNS drugs: Diazepam, citalopram, imipramine, clomipramine, phenytoin\u003cbr\u003e Antivirals: Atazanavir, saquinavir, nelfinavir (contraindicated)\u003cbr\u003e Others: Clopidogrel, digoxin, erlotinib, tacrolimus, methotrexate, clarithromycin\u003cbr\u003e Enzyme inducers\/inhibitors: Rifampicin, St. John’s Wort (CYP2C19 \u0026amp; CYP3A4)\u003cbr\u003eContraindications\u003cbr\u003e Known hypersensitivity to omeprazole, sodium bicarbonate, or substituted\u003cbr\u003ebenzimidazoles\u003cbr\u003e Concurrent use with nelfinavir\u003cbr\u003ePrecautions\u003cbr\u003e A positive response to treatment does not exclude gastric cancer; further evaluation\u003cbr\u003emay be needed if symptoms persist or worsen.\u003cbr\u003eWarnings\u003cbr\u003e1. Atrophic Gastritis: Observed in some long-term omeprazole users; monitor as needed.\u003cbr\u003e2. Sodium Bicarbonate Use: Caution in patients with:\u003cbr\u003eo Bartter’s syndrome\u003cbr\u003eo Hypokalemia\u003cbr\u003eo Respiratory alkalosis\u003cbr\u003eo Acid-base disturbances\u003cbr\u003eo Risk of milk-alkali syndrome when taken with calcium or milk long-term\u003cbr\u003e3. Sodium Content Alert: Contains sodium bicarbonate; use cautiously in patients on\u003cbr\u003esodium-restricted diets.\u003cbr\u003ePregnancy Category\u003cbr\u003e Consult a physician before use during pregnancy or breastfeeding.\u003cbr\u003eStorage\u003cbr\u003eYes\u003cbr\u003e Store at room temperature, protected from direct light and heat.\u003c\/p\u003e","brand":"The Wellness Hospital","offers":[{"title":"Default Title","offer_id":53280657572171,"sku":null,"price":477.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/5711\/6491\/files\/JA1_7216.jpg?v=1756546708","url":"https:\/\/wellnesspharmacy.pk\/products\/teph-capsules-40mg","provider":"The Wellness Hospital","version":"1.0","type":"link"}