Co-Diovan Tablets 160mg/12.5mg

Medicine Name: Co-Diovan Tablets 160mg/12.5mg

💊 Co-Diovan Tablets – Product Specification
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✅ Requires Prescription:
Yes
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🔬 Generics:
Valsartan + Hydrochlorothiazide
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📌 Used For:
•    Treatment of hypertension (high blood pressure)
•    Helps reduce the risk of cardiovascular events such as stroke and heart attack
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⚙️ How It Works:
•    Valsartan:
o    A selective angiotensin II receptor blocker (ARB)
o    Inhibits vasoconstriction and aldosterone secretion by blocking AT1 receptors
o    Lowers blood pressure by relaxing blood vessels
•    Hydrochlorothiazide (HCTZ):
o    A thiazide diuretic
o    Increases excretion of sodium and chloride → reduces plasma volume
o    Decreases cardiac output and lowers blood pressure
o    Causes potassium loss and mild diuresis
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💊 Dosage:
•    Active ingredients: Valsartan + Hydrochlorothiazide
•    Dosage strength varies (e.g., 80/12.5 mg, 160/12.5 mg, 160/25 mg)
•    Follow physician's instructions for appropriate dose
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⚠️ Side Effects:
Uncommon:
•    Dehydration
•    Paresthesia
•    Blurred vision
•    Tinnitus
•    Hypotension
•    Cough
•    Myalgia
•    Fatigue

Very Rare:
•    Dizziness
•    Diarrhea
•    Arthralgia
Frequency Unknown:
•    Syncope
•    Non-cardiogenic pulmonary edema
•    Impaired renal function
•    Increased uric acid, bilirubin, creatinine
•    Hypokalemia, hyponatremia
•    Elevated blood urea nitrogen (BUN)
•    Neutropenia
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🔄 Drug Interactions:
Use caution or avoid with:
•    Lithium, Methyldopa
•    NSAIDs, Rifampin, Cyclosporine, Ritonavir
•    Diuretics, Amphotericin, Carbenoxolone
•    Antidepressants, Antipsychotics, Antiepileptics
•    Allopurinol, Cholestyramine, Colestipol
•    Probenecid, Sulfinpyrazone, Tetracyclines
•    Alcohol, Sedatives, Anaesthetics
•    Potassium supplements or sparing agents
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💡 Indications:
•    Treatment of hypertension in patients for whom dual therapy is appropriate
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🚫 When Not to Use:
•    Known hypersensitivity to Valsartan, Hydrochlorothiazide, or sulfonamide-derived drugs
•    Severe hepatic impairment, biliary cirrhosis, cholestasis
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⚠️ Precautions:
•    Monitor volume status in salt-depleted patients before initiating therapy
•    Use with caution in patients with renal artery stenosis, electrolyte imbalance, or diabetes
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⚠️ Warnings:
Warning 1:
•    Risk of photosensitivity with hydrochlorothiazide. If it occurs, discontinue use and protect skin from sun/UV exposure.
Warning 2:
•    May trigger hypersensitivity reactions, especially in patients with allergy or asthma
Warning 3:
•    Can alter glucose tolerance and raise cholesterol/triglyceride levels
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👶 Pregnancy Category:
•    Not recommended in pregnancy
•    Always consult your doctor before use
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🏠 Storage:
✅ Yes — Store at room temperature, away from heat and direct light