Deprel Tablets 100mg

Medicine Name: Deprel Tablets 100mg

💊 Deprel Tablets – Product Information Sheet
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✅ Requires Prescription
Yes
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🧪 Generic Name
Trazodone Hydrochloride (HCl)
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🩺 Used For
Depression, including depression accompanied by anxiety
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⚙️ How It Works
Trazodone is a serotonin antagonist and reuptake inhibitor (SARI).
It:
•    Inhibits serotonin reuptake at high concentrations.
•    Exhibits antiserotonin, adrenergic blocking, and analgesic properties.
•    Has minimal anticholinergic activity compared to tricyclic antidepressants.
•    Aids in improving mood, reducing anxiety, and restoring emotional balance.
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📦 Dosage
•    Active Ingredient: Trazodone HCl
•    Dosage to be determined by a healthcare professional based on individual needs.
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⚠️ Side Effects
Serious:
•    Suicidal thoughts or behavior
•    Seizures
•    Serotonin Syndrome (confusion, hallucinations, tremors, fast heartbeat, fever)
•    Neuroleptic Malignant Syndrome (fever, muscle rigidity, altered consciousness)
•    Irregular heartbeat (tachycardia, bradycardia, arrhythmia)
Other Reported Effects:
•    Fatigue, dizziness, fainting
•    Numbness, tingling (paraesthesia)
•    Pale skin (possible anemia)
•    Drowsiness, blurred vision
•    Sweating, nausea
•    Mental confusion (especially in elderly)
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💊 Drug Interactions
Avoid concurrent use with:
•    MAOIs (e.g., tranylcypromine, selegiline)
•    Other antidepressants (e.g., fluoxetine, amitriptyline)
•    Sedatives, sleeping pills
•    Antiepileptics (e.g., carbamazepine, phenytoin)
•    Heart medications (e.g., digoxin, clonidine)
•    Antifungals (ketoconazole, itraconazole)
•    HIV treatments (ritonavir, indinavir)
•    Antibiotics (erythromycin)
•    Levodopa, St. John’s Wort, warfarin
•    Phenothiazines (e.g., chlorpromazine)
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🎯 Indication
Treatment of:
•    Major depressive disorder
•    Depression with anxiety
(Also used off-label for insomnia and chronic pain with physician oversight.)
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🚫 When Not to Use
Do not use Trazodone if:
•    You are allergic to trazodone or its ingredients.
•    You have recently had a heart attack.
•    You are a heavy alcohol user or using CNS depressants/sleep aids.
•    You are under 18 years of age.
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⚠️ Warnings
•    Warning 1 – Elderly: Increased sensitivity to side effects (e.g., dizziness, low BP, mental confusion).
•    Warning 2 – Suicidal Ideation: May worsen suicidal thoughts in early treatment phase.
•    Warning 3 – Sedation: May cause drowsiness; avoid driving or operating machinery until drug effects are known.
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🔍 Precaution
Do not stop medication suddenly. Gradual tapering is recommended to prevent withdrawal symptoms such as:
•    Sleep disturbances
•    Irritability
•    Excessive sweating
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🤰 Pregnancy Category
Consult your physician before use during pregnancy or breastfeeding.
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🧊 Storage
Yes
Store at room temperature, away from light, moisture, and heat.