Empagli Tablets 10mg

Medicine Name: Empagli Tablets 10mg

🩺 Empagli Tablets – Product Specification Sheet
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🔖 Requires Prescription
✅ Yes
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💊 Generic Name
Empagliflozin (SGLT2 Inhibitor)
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⚕️ Used For
Type 2 Diabetes Mellitus
As monotherapy when metformin is not tolerated
As add-on therapy with other antidiabetic agents including insulin
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⚙️ Mechanism of Action
Empagliflozin inhibits Sodium-Glucose Co-Transporter 2 (SGLT2) in the kidney
Reduces renal glucose reabsorption, lowers renal glucose threshold
Increases urinary glucose excretion, thereby reducing plasma glucose levels independently of insulin
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💉 Dosage
As prescribed by a physician
May be used as monotherapy or in combination
Adjust dose based on renal function and glycemic response
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⚠️ Side Effects
Frequency    Side Effects
Very Common    Hypoglycemia (especially with sulphonylurea or insulin)
Common    Genital infections (e.g. vulvovaginitis, balanitis), UTI, pruritus, polyuria
Uncommon    Volume depletion, dysuria, elevated creatinine/reduced GFR
Rare    Diabetic ketoacidosis (DKA)
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🔄 Drug Interactions
Diuretics, especially thiazides and loop diuretics → may increase risk of dehydration and hypotension
Other SGLT2 inhibitors → avoid duplication
Use caution in combination with insulin or sulphonylureas due to hypoglycemia risk
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📌 Indications
✅ Monotherapy
For patients intolerant to metformin where diet and exercise alone are insufficient
✅ Add-On Therapy
With other antidiabetic medications (e.g. insulin, metformin) when glycemic control is not achieved
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🚫 Contraindications (When Not to Use)
Known hypersensitivity to empagliflozin or formulation components
Severe renal impairment, end-stage renal disease, or patients on dialysis
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⚠️ Precautions
Increased risk of volume depletion and symptomatic hypotension, particularly in:
Elderly patients
Patients with renal impairment
Those with low systolic BP
Patients on diuretics
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⚠️ Warnings
Hypoglycemia
Risk increased when combined with insulin or sulphonylureas
Consider dose reduction of insulin or secretagogue if combined
Urinary Tract Infections (UTIs)
May increase risk of serious UTIs (e.g. pyelonephritis, urosepsis)
Monitor and discontinue if infections recur
Diabetic Ketoacidosis (DKA)
Not indicated for type 1 diabetes or DKA
Discontinue immediately if DKA is suspected
Temporarily interrupt in cases of surgery, hospitalization, or acute illness
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👶 Pregnancy Category
Always consult a physician before use in pregnancy
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📦 Storage Required
✅ Yes
Store at room temperature
Keep away from direct light, heat, and moisture