Entamizole 90Ml Suspension 250mg/200mg

Requires Prescription:
✅ Yes
Generics (Per 5 mL):
 Diloxanide Furoate – 250 mg
 Metronidazole – 200 mg
Used For:
 Bacterial and parasitic infections
 Particularly effective for intestinal and hepatic amoebiasis, and giardiasis
How It Works:
 Metronidazole: Inhibits DNA synthesis in anaerobic bacteria and protozoa, leading to
cell death.
 Diloxanide Furoate: Acts as a luminal amoebicide by blocking the energy production of
Entamoeba histolytica.
Together, they eliminate both tissue-dwelling and intestinal forms of the parasite.
Usage and Safety
Dosage:
 As prescribed by a physician
 Follow complete course to avoid recurrence or resistance
Side Effects:
 Gastrointestinal upset
 Metallic taste (dysgeusia)
 Leucopenia
 Urticaria, angioedema
 CNS disturbances (dizziness, headache)
 Dark-colored urine
 Neuropathy and seizures (with long-term use)
 Severe skin reactions (e.g., Stevens-Johnson Syndrome)
Drug Interactions:
Avoid combining with:
 Alcohol (causes disulfiram-like reaction)
 Warfarin and other anticoagulants (increased bleeding risk)
 Phenytoin, Phenobarbital (may reduce effectiveness)
 Lithium (risk of toxicity)
Indications:
Treatment of:
 Acute and chronic amoebiasis
 Hepatic amoebiasis
 Giardiasis
 Other systemic infections caused by E. histolytica
When Not to Use:
 Known hypersensitivity to Diloxanide, Metronidazole, or other nitroimidazoles
 Patients with:
o History of seizures
o Chronic alcoholism
o Severe liver disease
o Peripheral neuropathy
Precautions:
 Use cautiously in liver dysfunction, renal impairment, and blood disorders
 Avoid alcohol during and 48 hours after use
 Monitor for signs of CNS toxicity with prolonged use
Warnings:
Warning 1:
Disclose full medical history (esp. liver/kidney issues, seizures, or blood disorders) to the
prescribing doctor.
Warning 2:
Use in pregnancy only when clearly needed. Consult physician.
Warning 3:
Can cause drowsiness/dizziness—avoid driving or operating machinery until effects are known.
Pregnancy Category:
⚠️ Consult your physician before using during pregnancy or breastfeeding
Storage (YES/NO):
✅ Yes – Store at room temperature, away from direct light and heat