Entamizole Tablets 250mg/200mg

Medicine Name: Entamizole Tablets 250mg/200mg

Entamizole Tablets Specification
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Requires Prescription
Yes
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Generics
Diloxanide Furoate
Metronidazole
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Used For
Bacterial and Protozoal Infections, including:
Acute Amoebiasis
Chronic Amoebiasis
Hepatic Amoebiasis
Giardiasis
Systemic infections due to Entamoeba histolytica
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How It Works
Diloxanide Furoate acts as a luminal amoebicide, effective against E. histolytica in the intestine.
Metronidazole is an antiprotozoal and antibacterial agent that inhibits nucleic acid synthesis by disrupting the DNA of microbial cells, effectively killing anaerobic bacteria and parasites.
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Usage and Safety
Dosage
Contains Diloxanide Furoate and Metronidazole
Dose as prescribed by a healthcare provider based on infection severity and patient condition
Side Effects
Common: GI upset, metallic taste (dysgeusia), dark urine
Less Common: Leucopenia, urticaria, angioedema, CNS disturbances
Rare/Severe: Peripheral neuropathy, epileptiform seizures (with long-term use), severe bullous skin reactions
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Drug Interactions
Alcohol (risk of disulfiram-like reaction)
Anticoagulants (e.g., warfarin – may enhance effect)
Phenobarbital, phenytoin (altered metronidazole levels)
Lithium (risk of lithium toxicity)
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Indications
Treatment of:
Intestinal and hepatic amoebiasis
Giardiasis
Systemic amoebic infections caused by E. histolytica
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When Not to Use
Contraindicated in:
Known hypersensitivity to metronidazole, diloxanide furoate, or excipients
Liver disease
Alcohol use disorder or current alcohol consumption
Seizure disorders or history of seizures
Peripheral neuropathy (pain or tingling in hands/feet)
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Precautions
Inform your physician if you have allergies, especially to other antibiotics like tinidazole
Monitor closely in patients with blood disorders, renal, or hepatic impairment
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Warnings
Warning 1 – Organ Function
Use with caution in patients with liver, kidney, or blood disorders.
Warning 2 – Pregnancy
Should only be used during pregnancy if clearly needed. Consult your doctor to weigh risks and benefits.
Warning 3 – Neurological Effects
May cause drowsiness, dizziness, or confusion. Avoid driving or operating machinery until you know how the medicine affects you.
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Additional Information
Pregnancy Category
Always consult your physician before use
Storage (YES/NO)
Yes – Store at room temperature, protected from light and heat