Exforge Tablets 5/160mg

Medicine Name: Exforge Tablets 5/160mg

📋 Exforge Tablets – Product Specification
________________________________________
✅ Requires Prescription
Yes
________________________________________
💊 Generics
Amlodipine Besilate + Valsartan
________________________________________

🩺 Used For
Hypertension (High Blood Pressure)
________________________________________
⚙️ How It Works
•    Amlodipine is a calcium channel blocker that relaxes blood vessels.
•    Valsartan is an angiotensin II receptor blocker (ARB) that prevents vasoconstriction.
•    Together, they provide complementary mechanisms to effectively reduce blood pressure more than either alone.
________________________________________
📦 Dosage
Amlodipine Besilate + Valsartan
Dosage to be prescribed by a healthcare provider based on individual patient needs.
________________________________________
⚠️ Side Effects
Common side effects may include:
•    Infections & Flu-like symptoms: Nasopharyngitis, influenza
•    Neurological: Headache, dizziness, vertigo, somnolence, paraesthesia
•    Cardiovascular: Hypotension (including postural), palpitations, tachycardia, facial and peripheral edema, flushing
•    Gastrointestinal: Nausea, abdominal pain, dry mouth, constipation, diarrhea
•    Musculoskeletal: Back pain, joint swelling, arthralgia
•    Electrolyte/Metabolic: Hypokalemia, hyponatremia, hyperlipidemia, hyperuricemia
•    Skin: Rash, erythema
________________________________________
💊 Drug Interactions
Use cautiously with:
•    Other antihypertensives
•    Grapefruit juice (affects drug metabolism)
•    CYP3A4 inhibitors/inducers (e.g. erythromycin, ketoconazole, rifampicin)
•    Simvastatin (may increase levels)
•    Lithium, NSAIDs, Sildenafil
•    Potassium-altering agents (e.g. potassium-sparing diuretics, supplements, heparin)
________________________________________
🎯 Indication
•    Treatment of essential hypertension where dual therapy is appropriate.
________________________________________
🚫 When Not to Use
Contraindicated in patients with:
•    Hypersensitivity to amlodipine, valsartan, dihydropyridines, or excipients
•    Severe hepatic impairment, biliary cirrhosis, or cholestasis
________________________________________
🔍 Precautions
•    Use with caution in patients with renal artery stenosis, especially unilateral or in a solitary kidney – may lead to elevated creatinine or urea levels.
________________________________________
⚠️ Warnings
•    Warning 1: Monitor potassium when using with potassium-sparing diuretics or supplements.
•    Warning 2: Not established for use in hypertensive crises.
•    Warning 3: Angioedema risk—discontinue immediately if symptoms appear; do not reinitiate.
________________________________________
🤰 Pregnancy Category
Always consult your physician before use.
Valsartan is contraindicated during pregnancy due to fetal risk.
________________________________________

🧊 Storage
Yes
Store at room temperature, away from light, moisture, and heat.