Extor Tablets 10/160mg

Medicine Name: Extor Tablets 10/160mg

Extor Tablets – Product Specification
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✅ Requires Prescription
Yes
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💊 Generics
Amlodipine Besilate + Valsartan
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🩺 Used For
•    Treatment of Hypertension (high blood pressure)
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⚙️ How It Works
•    Amlodipine is a calcium channel blocker that relaxes blood vessels, allowing blood to flow more easily.
•    Valsartan is an angiotensin II receptor blocker (ARB) that prevents the narrowing of blood vessels.
•    Together, they provide additive blood pressure-lowering effects greater than either component alone.
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📋 Dosage
•    Active Ingredients: Amlodipine Besilate + Valsartan
•    Dosage and duration should be determined by a healthcare provider based on the patient's condition.
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⚠️ Side Effects
•    Common:
Nasopharyngitis, influenza, headache, dizziness, fatigue, flushing, edema (including peripheral and facial), nausea, abdominal discomfort, diarrhea, constipation, dry mouth.
•    Less Common/Serious:
Hypokalemia, hyperkalemia, hyponatremia, palpitations, orthostatic hypotension, visual disturbances, rash, joint swelling, vertigo, somnolence, paraesthesia, tachycardia, back pain, and aggravated joint pain.
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🔄 Drug Interactions
•    Increased risk or altered efficacy with:
o    Grapefruit or grapefruit juice
o    CYP3A4 inhibitors: e.g., erythromycin, ketoconazole
o    CYP3A4 inducers: e.g., rifampicin, St. John’s Wort
o    Lithium (risk of toxicity)
o    NSAIDs (may reduce antihypertensive effect)
o    Simvastatin
o    Potassium-altering agents: potassium-sparing diuretics, supplements, salt substitutes
o    Sildenafil, ritonavir, cyclosporine
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📌 Indication
•    Indicated for the management of high blood pressure, especially in patients requiring dual therapy.
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🚫 When Not to Use
•    Known hypersensitivity to amlodipine, valsartan, dihydropyridines, or excipients
•    Severe hepatic impairment
•    Biliary cirrhosis or cholestasis
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🛡️ Precautions
•    Use with caution in:
o    Renal artery stenosis (especially in a solitary kidney)
o    Kidney dysfunction
o    Volume-depleted patients
o    Monitor renal function and electrolyte levels
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⚠️ Warnings
1.    Potassium Monitoring
Regular monitoring is essential when used with potassium-altering medications.
2.    Not for Hypertensive Crisis
The efficacy of amlodipine in managing hypertensive emergencies is not established.
3.    Angioedema Risk
Discontinue immediately if angioedema occurs; do not reinitiate therapy.
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🤰 Pregnancy Category
•    Use only if prescribed. Avoid during pregnancy unless essential. Consult your doctor.
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🧴 Storage
Yes
•    Store at room temperature
•    Keep away from direct light, moisture, and heat