Icon Capsules 100MG

Medicine Name: Icon Capsules 100mg
✅ Icon Capsules – Product Specification
📌 Requires Prescription:
Yes
💊 Generic Name:
Itraconazole
⚕️ Used For:
 Fungal infections including:
o Vaginal yeast infections
o Dermatological (skin) fungal infections
o Onychomycosis (nail fungal infections)
o Oral and esophageal candidiasis
⚙️ How It Works:
Itraconazole is an antifungal agent belonging to the triazole class.
It works by inhibiting fungal cytochrome P450 enzymes, impairing ergosterol synthesis,
which is a vital component of fungal cell membranes. This leads to slowed growth or death of
the fungus.
⚕️ Dosage:
 Active Ingredient: Itraconazole
 Dosage as directed by physician depending on indication, severity, and patient profile.
⚠️ Side Effects:
🔸 Hematologic/Metabolic:
 Granulocytopenia
 Thrombocytopenia
 Hyperglycemia
 Hyperkalemia / Hypokalemia
 Hypomagnesemia
🔸 Neurological:
 Dizziness
 Somnolence
 Peripheral neuropathy
 Confusional state
🔸 Cardiovascular:
 Congestive heart failure (CHF)
 Tachycardia
 Hypertension / Hypotension
🔸 Gastrointestinal & Hepatic:
 GI upset
 Hepatitis
 Hepatic failure
 Jaundice
🔸 Dermatologic / Musculoskeletal / Other:
 Erythematous rash
 Hyperhidrosis
 Myalgia / Arthralgia
 Edema (general or facial)
 Chest pain
 Fatigue
 Fever
 Chills
🔄 Drug Interactions:
Itraconazole has many potential serious drug interactions, especially with drugs metabolized by
CYP3A4.
Major interactions include:
 Rifampicin, Cyclosporin, Tacrolimus, Sirolimus
 Statins, Digoxin, Domperidone, Ergot alkaloids
 H2 antagonists, Antacids
 Tamsulosin, Ivabradine, Meloxicam
 Midazolam, Reboxetine, Salmeterol, Nadolol
 Saxagliptin, Repaglinide, Tolvaptan
🚫 When Not to Use:
 Known hypersensitivity to Itraconazole or any formulation component
 Use with caution or avoid in heart failure patients
 Use in pregnancy is contraindicated unless absolutely necessary
⚖️ Precautions:
 May cause dizziness, visual or hearing disturbances
 Patients should be cautious when driving or operating machinery
⚠️ Warnings:
1. Congestive Heart Failure (CHF):
Itraconazole has a negative inotropic effect—avoid in patients with ventricular
dysfunction or history of CHF.
2. Hypersensitivity Risk:
Limited data exist on cross-reactivity with other azoles; caution advised if allergic to
other antifungals (e.g. fluconazole, ketoconazole).
3. Pediatric Use:
Not generally recommended in children unless benefits outweigh risks.
🤰 Pregnancy Category:
Always consult your physician. Itraconazole is contraindicated during pregnancy unless no
safer alternative exists and the infection is serious.
⚕️ Storage:
Yes
 Store at room temperature
 Protect from light and heat