Maxflow-D Capsules 0.5MG/0.4MG

Medicine Name: Maxflow-D Capsules 0.5mg/0.4mg

✅Maxflow-D Capsules – Product Specification
📌 Requires Prescription:
Yes

💊 Generics:
Tamsulosin HCl + Dutasteride
⚕️ Used For:
Benign Prostatic Hyperplasia (BPH) – an enlarged prostate, with the following benefits:
 Relieves urinary symptoms
 Reduces prostate size
 Improves urine flow
 Reduces risk of acute urinary retention (AUR)
 Lowers the need for BPH-related surgery
⚙️ How It Works:
 Tamsulosin HCl:
Selectively blocks α1A and α1D adrenergic receptors in the prostate and bladder
neck, relaxing smooth muscles and easing urinary flow.
 Dutasteride:
Inhibits 5-alpha-reductase type 1 and 2 enzymes, preventing the conversion of
testosterone to dihydrotestosterone (DHT). DHT is responsible for prostate growth.
Reducing DHT shrinks the prostate and slows disease progression.
⚕️ Dosage:
Tamsulosin HCl + Dutasteride
 Taken once daily, after the same meal each day.
 Dosage as per physician’s recommendation.
⚠️ Side Effects:
🔸 Common:
 Dizziness
 Impotence
 Decreased libido
 Ejaculation disorders (e.g. retrograde ejaculation)
 Breast disorders (e.g. tenderness, enlargement)
🔸 Uncommon:
 Cardiac failure
🔄 Drug Interactions:
Use caution with:
 Strong CYP3A4 inhibitors (e.g. ketoconazole, erythromycin)
 Moderate CYP3A4 inhibitors (e.g. terbinafine)
 Strong CYP2D6 inhibitors (e.g. paroxetine)
 Cimetidine
 Warfarin (monitor INR)
 PDE-5 inhibitors (e.g. sildenafil, tadalafil) – risk of hypotension
🚫 When Not to Use:
Do not use in:
 Known hypersensitivity to dutasteride, tamsulosin, soya, peanut, or any formulation
ingredient
 Women, children, and adolescents
 Severe hepatic impairment
 History of orthostatic hypotension
⚖️ Precautions:
 Prescribe only after risk-benefit assessment, particularly due to possible cardiac
adverse events
 Consider monotherapy options if suitable
⚠️ Warnings:
1. Prostate cancer monitoring:
Patients should be regularly evaluated to rule out prostate cancer.
2. Renal impairment:
Use with caution in patients with creatinine clearance <10 ml/min
3. Orthostatic hypotension:
Inform patients of potential dizziness or fainting on standing quickly
🤰 Pregnancy Category:
Contraindicated in women.
 Dutasteride is absorbed through the skin—women of childbearing potential must avoid
contact with capsules.
⚕️ Storage (YES/NO):
Yes
 Store at room temperature, protected from light and heat