Savesto 50 Tablets 24/26mg

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Sale price Rs.1,322.16 PKRRegular price Rs.1,391.88 PKR
Regular price Rs.1,322.16 PKR
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Natural ingredients

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Sacubitril + valsartan inhibits neprilysin (neutral endopeptidase; NEP) , the active metabolite of the prodrug sacubitril and blocks the angiotensin II type-1 (AT1) receptor via valsartan. The cardiovascular and renal effects of sacubitril + valsartan in heart failure patients are attributed to the increased levels of peptides that are degraded by neprilysin, such as natriuretic peptides (NPs) and the simultaneous inhibition of the effects of angiotensin II by valsartan.

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